English Title: Examinations of Microglia and the Mannose-Receptor under a immunological point of view
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Abstract
Die Rolle des Mannose-Rezeptors in Mikroglia-Zellen wurde untersucht. Durch Stimulation mit Cytokinen wurde die Regulation der Expression und Aktivität des Mannose-Rezeptors in einem immunologischen Umfeld in Mikroglia-Zellen simuliert. Die erhaltenen Ergebnissse sprechen für eine Beteiligung des Mannose-Rezeptors an der immunologisch relevanten Aktivität der Mikroglia-Zellen.
Translation of abstract (English)
The role of the mannose receptor in microglia was examined. Immunological conditions were simulated by stimulating the microglia with cytokines and the regulation of expression and function of the mannose receptor under these conditions was analysed. The results lead to the conclusion that the mannose receptor is involved in immunological funtions of microglia cells.
| Document type: | Dissertation |
|---|---|
| Supervisor: | Régnier-Vigouroux, Anne PD |
| Date of thesis defense: | 31 May 2002 |
| Date Deposited: | 24 Jun 2002 00:00 |
| Date: | 2002 |
| Faculties / Institutes: | Service facilities > Interdisziplinäres Zentrum für Neurowissenschaften |
| DDC-classification: | 570 Life sciences |
| Uncontrolled Keywords: | Mikroglia-Zellen , Mannose-Rezeptor , Cytokine , Endocytose , PhagocytoseMicroglia , Mannose-Receptor , Cytokines , Endocytosis , Phagocytosis |
