Article

Vogt, Anne B. ; Stern, Lawrence J. ; Amshoff, Christine ; Dobberstein, Bernhard ; Hämmerling, Günter J. ; Kropshofer, Harald (1995) Interference of Distinct Invariant Chain Regions with Superantigen Contact Area and Antigenic Peptide Binding Groove of HLA-DR. The Journal of Immunology , 155. pp. 4757-4765.

Martoglio, Bruno ; Dobberstein, Bernhard (1995) Protein insertion into the membrane of the endoplasmic reticulum: The architecture of the translocation site. Cold Spring Harbor Symposia on Quantitative Biology, LX. pp. 41-45.

Martoglio, Bruno ; Hofmann, Michael W. ; Brunner, Josef ; Dobberstein, Bernhard (1995) The Protein-Conducting Channel in the Membrane of the Endoplasmic Reticulum Is Open Laterally toward the Lipid Bilayer. Cell, 81. pp. 207-214.

Lyko, Frank ; Martoglio, Bruno ; Jungnickel, Berit ; Rapoport, Tom A. ; Dobberstein, Bernhard (1995) Signal Sequence Processing in Rough Microsomes. The Journal of Biological Chemistry, 270 (34). pp. 19873-19878.

Hauser, Stefanie ; Bacher, Gerald ; Dobberstein, Bernhard ; Lütcke, Henrich (1995) A complex of the signal sequence binding protein and the SRP RNA promotes translocation of nascent proteins. The EMBO Journal, 14 (22). pp. 5485-5493.

Lentzen, Georg ; Dobberstein, Bernhard ; Wintermeyer, Wolfgang (1994) Formation of SRP-like particle induces a conformational change in E. coli 4.5S RNA. FEBS Letters, 348. pp. 233-238.

Luirink, Joen ; Dobberstein, Bernhard (1994) Mammalian and Escherichia coli signal recognition particles. Molecular Microbiology, 11. pp. 9-13.

Dobberstein, Bernhard (1994) Protein transport: On the beaten pathway. Nature, 367. pp. 599-600.

Joen, Luirink ; ten Hagen-Jongman, Corinne M. ; van der Weijden, Coen C. ; Oudega, Bauke ; High, Stephen ; Dobberstein, Bernhard ; Kusters, Ron (1994) An alternative protein targeting pathway in Escherichia coli: studies on the role of FtsY. The EMBO Journal, 13 (10). pp. 2289-2296.

Lütcke, Henrich ; Prehn, Siegfried ; Ashford, Anthony J. ; Remus, Michael ; Frank, Rainer ; Dobberstein, Bernhard (1993) Assembly of the 68- and 72-kD Proteins of Signal Recognition Particle with 7S RNA. The Journal of Cell Biology, 121 (5). pp. 977-985.

Lütcke, Henrich ; Prehn, Siegfried ; Ashford, Anthony J. ; Remus, Michael ; Frank, Rainer ; Dobberstein, Bernhard (1993) Assembly of the 68- and 72-kD Proteins of Signal Recognition Particle with 7S RNA. The Journal of Cell Biology, 121 (5). pp. 977-985.

Pieters, Jean ; Bakke, Oddmund ; Dobberstein, Bernhard (1993) The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail. Journal of Cell Science, 106. pp. 831-846.

High, Stephen ; Andersen, Soren S. L. ; Görlich, Dirk ; Hartmann, Enno ; Prehn, Siegfried ; Rapoport, Tom A. ; Dobberstein, Bernhard (1993) Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion. The Journal of Cell Biology, 121 (4). pp. 743-750.

High, Stephen ; Martoglio, Bruno ; Görlich, Dirk ; Andersen, Soren S. L. ; Ashford, Anthony J. ; Giner, Angelika ; Hartmann, Enno ; Prehn, Siegfried ; Rapoport, Tom A. ; Dobberstein, Bernhard ; Brunner, Josef (1993) Site-specific Photocross-linking Reveals That SecGlp and TRAM Contact Different Regions of a Membrane-inserted Signal Sequence. The Journal of Biological Chemistry, 268 (35). pp. 26746-2671.

High, Stephen ; Dobberstein, Bernhard (1992) Mechanisms that determine the transmembrane disposition of proteins. Current Opinion Cell Biology, 4. pp. 581-586.

Luirink, Joen ; High, Stephen ; Wood, Heather ; Giner, Angelika ; Tollervey, David ; Dobberstein, Bernhard (1992) Signal-sequence recognition by an Escherichia coli ribonucleoprotein complex. Nature, 359. pp. 741-743.

Dobberstein, Bernhard (1992) Who needs peptide transporters. Nature, 355. pp. 109-110.

Zachgo, Sabine ; Dobberstein, Bernhard ; Griffiths, Gareth (1992) A block in degradation of MHC class II-associated invariant chain correlates with a reduction in transport from endosome carrier vesicles to the prelysosome compartment. Journal of Cell Science, 103. pp. 811-822.

Zachgo, Sabine ; Dobberstein, Bernhard ; Griffiths, Gareth (1992) A block in degradation of MHC class II-associated invariant chain correlates with a reduction in transport from endosome carrier vesicles to the prelysosome compartment. The Journal of Cell Science, 103. pp. 811-822.

Lütcke, Henrich ; High, Stephen ; Römisch, Karin ; Ashford, Anthony J. ; Dobberstein, Bernhard (1992) The methionine-rich domain of the 54 kDa subunit of signal recognition particle is sufficient for the interaction with signal sequences. The EMBO Journal, 11 (4). pp. 1543-1551.

High, Stephen ; Görlich, Dirk ; Wiedmann, Martin ; Rapoport, Tom A. ; Dobberstein, Bernhard (1991) The Identification of Proteins in the Proximity of Signal-Anchor Sequences during Their Targeting to and Insertion into the Membrane of the ER. The Journal of Cell Biology, 113 (1). pp. 35-44.

High, Stephen ; Flint, Nicholas ; Dobberstein, Bernhard (1991) Requirements for the Membrane Insertion of Signal-anchor Type Proteins. The Journal of Cell Biology, 113 (1). pp. 25-34.

High, Stephen ; Dobberstein, Bernhard (1991) The Signal Sequence Interacts with the Methionine-rich Domain of the 54-kD Protein of Signal Recognition Particle. The Journal of Cell Biology , 113 (2). pp. 223-233.

Römisch, Karen ; Webb, Jane ; Lingelbach, Klaus ; Gausepohl, Heinrich ; Dobberstein, Bernhard (1990) The 54-kD Protein of Signal Recognition Particle Contains a Methionine-rich RNA Binding Domain. The Journal of Cell Biology, 111. pp. 1793-1802.

Herz, Joachim ; Flint, Nicholas ; Stanley, Keith ; Frank, Rainer ; Dobberstein, Bernhard (1990) The 68 kDa protein of signal recognition particle contains a glycine-richregion also found in certain RNA-binding proteins. FEBS Letters , 276 (1,2). pp. 103-107.

Ribes, Veronique ; Römisch, Karin ; Giner, Angelika ; Dobberstein, Bernhard ; Tollervey, David (1990) E. coli 4.5S RNA is part of a ribonucleoprotein particle that has properties related to signal recognition particle. Cell, 63. pp. 591-600.

Bakke, Oddmund ; Dobberstein, Bernhard (1990) MHC class II-associated invariant chain contains a sorting signal for endosomal compartments. Cell, 63. pp. 707-716.

Görlich, Dirk ; Prehn, Siegfried ; Hartmann, Enno ; Herz, Joachim ; Otto, Albrecht ; Kraft, Regine ; Wiedmann, Martin ; Knespel, Siegne ; Dobberstein, Bernhard ; Rapoport, Tom A. (1990) The Signal Sequence Receptor Has a Second Subunit and IsPart of a Translocation Complex in the Endoplasmic Reticulum as Probed by Bifunctional Reagents. The Journal of Cell Biology, 111 (6). pp. 2283-2294.

Prehn, Siegfried ; Herz, Joachim ; Hartmann, Enno ; Kurzchalia, Teymuras V. ; Frank, Rainer ; Römisch, Karin ; Dobberstein, Bernhard ; Rapoport, Tom A. (1990) Structure and biosynthesis of the signal-sequence receptor. European Journal of Biochemistry, 188. pp. 439-445.

Römisch, Karin ; Ribes, Veronique ; High, Stephen ; Lütcke, Henrich ; Tollervey, David ; Dobberstein, Bernhard (1990) Structure and function of signal recognition particle (SRP). Molecular Biology Reports, 14. pp. 71-72.

Römisch, Karin ; Webb, Jane ; Herz, Joachim ; Prehn, Siegfried ; Frank, Rainer ; Vingron, Martin ; Dobberstein, Bernhard (1989) Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains. Nature, 340. pp. 478-482.

Koch, Norbert ; Lipp, Joachim ; Pessara, Ulrich ; Schenck, Klaus ; Wraight, Christopher ; Dobberstein, Bernhard (1989) MHC class II invariant chains in antigen processing and presentation. Trends in biochemical sciences, 14. pp. 383-386.

Lipp, Joachim ; Flint, Nicholas ; Haeuptle, Marie-Theres ; Dobberstein, Bernhard (1989) Structural Requirements for Membrane Assembly of Proteins Spanning the Membrane Several Times. The Journal of Cell Biology, 109. pp. 2013-2022.

Haeuptle, Marie-Theres ; Flint, Nicholas ; Gough, Nicholas M. ; Dobberstein, Bernhard (1989) A Tripartite Structure of the Signals that Determine Protein Insertion into the Endoplasmic Reticulum Membrane. The Journal of Cell Biology, 108. pp. 1227-1236.

Lipp, Joachim ; Dobberstein, Bernhard (1988) Signal and Membrane Anchor Functions Overlap in the Type II Membrane Protein IgCAT. The Journal of Cell Biology, 106. pp. 1813-1820.

Lingelbach, Klaus ; Dobberstein, Bernhard (1988) An extended RNA/RNA duplex structure within the coding region of mRNA does not block translational elongation. Nucleic Acids Research, 16. pp. 3405-3414.

Scoulica, Efstathia ; Krause, Elke ; Meese, Klaus ; Dobberstein, Bernhard (1987) Disassembly and domain structure of the proteins in the signal-recognition particle. European Journal of Biochemistry, 1987 (163). pp. 519-528.

Koch, Norbert ; Lauer, Wolfgang ; Habicht, Jüri ; Dobberstein, Bernhard (1987) Primary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin. The EMBO Journal, 6 (6). pp. 1677-1683.

Lipp, Joachim ; Dobberstein, Bernhard ; Haeuptle, Marie-Theres (1987) Signal Recognition Particle Arrests Elongation of Nascent Secretory and Membrane Proteins at Multiple Sites in a Transient Manner. The Journal of Biological Chemistry, 262 (4). pp. 1680-1684.

Bujard, Hermann ; Gentz, Reiner ; Lanzer, Michael ; Stueber, Dietrich ; Mueller, Michael ; Ibrahimi, Ibrahim ; Haeuptle, Marie-Theres ; Dobberstein, Bernhard (1987) A T5 promoter-based transcription-translation system for the analysis of proteins in vitro and in vivo. Methods in Enzymology, 155. pp. 416-433.

Lipp, Joachim ; Dobberstein, Bernhard (1986) Signal Recognition Particle-dependent Membrane Insertion of Mouse Invariant Chain: A Membrane-spanning Protein with a Cytoplasmically Exposed Amino Terminus. The Journal of Cell Biology, 102. pp. 2169-2175.

Lipp, Joachim ; Dobberstein, Bernhard (1986) The membrane-spanning segment of invariant chain (I gamma) contains a potentially cleavable signal sequence. Cell, 46. pp. 1103-1112.

Spena, A. ; Krause, E. ; Dobberstein, Bernhard (1985) Translation efficiency of zein mRNA is reduced by hybrid formation between the 5´-and 3´-untranslated region. The EMBO Journal , 4 (9). pp. 2153-2158.

Singer, Paul A. ; Lauer, Wolfgang ; Dembic, Zlatko ; Mayer, Werner E. ; Lipp, Joachim ; Koch, Norbert ; Hämmerling, Günter ; Klein, Jan ; Dobberstein, Bernhard (1984) Structure of the murine Ia-associated invariant (Ii) chain as deduced from a cDNA clone. The EMBO Journal, 3 (4). pp. 873-877.

Stüber, Dietrich ; Ibrahimi, Ibrahim ; Cutler, Daniel ; Dobberstein, Bernhard ; Bujard, Herrmann (1984) A novel in vitro transcription-translation system: accurate and efficient synthesis of single proteins from cloned DNA sequences. The EMBO Journal, 3 (13). pp. 3143-3148.

Dobberstein, Bernhard ; Kvist, Sune (1983) Assembly of histocompatibility antigens. Methods in Enzymology, 96. pp. 325-331.

Kvist, S. ; Roberts, L . ; Dobberstein, Bernhard (1983) Mouse histocompatibility genes: structure and organisation of a Kd gene. The EMBO Journal, 2 (2). pp. 245-254.

Meyer, David I. ; Dobberstein, Bernhard (1983) Proteins mediating vectorial translocation: Purification of the active domain of the endoplasmic reticulum docking protein. Methods in Enzymology, 96. pp. 692-700.

Gundelfinger, Eckart D. ; Krause, Elke ; Melli, Marialuisa ; Dobberstein, Bernhard (1983) The organization of the 7SL RNA in the signal recognition particle. Nucleic Acids Research, 11 (21). pp. 7363-7374.

Meyer, David I. ; Louvard, Daniel ; Dobberstein, Bernhard (1982) Characterization of Molecules Involved in Protein Translocation Using a Specific Antibody. The Journal of Cell Biology, 92. pp. 579-583.

Kvist, Sune ; Wilman, Klas ; Claesson, Lena ; Peterson, Per A. ; Dobberstein, Bernhard (1982) Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens. Cell, 29. pp. 61-69.

Meyer, David I. ; Krause, Elke ; Dobberstein, Bernhard (1982) Secretory protein translocation across membranes - the role of the 'docking protein'. Nature, 297. pp. 647-650.

Meyer, David I. ; Dobberstein, Bernhard (1980) Identification and Characterization of a Membrane Component Essential for the Translocation of Nascent Proteins across the Membrane of the Endoplasmic Reticulum. THE JOURNAL OF CELL BIOLOGY , 87. pp. 503-508.

Meyer, David I. ; Dobberstein, Bernhard (1980) A Membrane Component Essential for Vectorial Translocation of Nascent Proteins across the Endoplasmic Reticulum: Requirements for Its Extraction and Reassociation with the Membrane. THE JOURNAL OF CELL BIOLOGY, 87. pp. 498-502.

Dobberstein, Bernhard ; Garoff, Henrik ; Warren, Graham (1979) Cell-free synthesis and membrane insertion of mouse H-2Dd histocompatibility antigen and beta2-microglobulin. Cell, 17. pp. 759-769.

Garoff, Henrik ; Simons, Kai ; Dobberstein, Bernhard (1978) Assembly of Semliki Forest virus membrane glycoprotein in the membrane of the endoplasmic reticulum in vitro. Journal of molecular biology 1978, 124. pp. 587-600.

Warren, Graham ; Dobberstein, Bernhard (1978) Protein transfer across microsomal membranes reassembled from separated membrane components. Nature, 273. pp. 569-571.

Scheele, George ; Dobberstein, Bernhard ; Blobel, Günter (1978) Transfer of Proteins across Membranes Biosynthesis in vitro of Pretrypsinogen and Trypsinogen by Cell Fractions of Canine Pancreas. European Journal of Biochemistry, 82. pp. 593-599.

Dobberstein, Bernhard ; Blobel, Günter (1977) Functional interaction of plant ribosomes with animal microsomal membranes. Biochemical and Biophysical Research Communications, 74 (4). pp. 1675-1682.

Dobberstein, Bernhard ; Blobel, Günter ; Chua, Nam-Hai (1977) In vitro synthesis and processing of a putative precursor for the small subunit of ribulose- 1,5-bisphosphate carboxylase of Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA, 74 (3). pp. 1082-1085.

Sehgal, Pravinkumar B. ; Dobberstein, Bernhard ; Tamm, Igor (1977) Interferon messenger RNA content of human fibroblasts during induction, shutoff, and superinduction of interferon production. Proc. Natl. Acad. Sci. USA, 74 (8). pp. 3409-3413.

Blobel, Günter ; Dobberstein, Bernhard (1975) Transfer of Proteins across Membranes II. Reconstitution of Functional RoughMicrosomes from Heterologous Components. The Journal of Cell Biology , 67. pp. 852-862.

Blobel, Günter ; Dobberstein, Bernhard (1975) Transfer of proteins across membranes I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. The Journal of Cell Biology, 67. pp. 835-851.

Dobberstein, Bernhard ; Volkmann, D. ; Klämbt, D. (1974) The attachment of polyribosomes to membranes of the hypocotyl of phaseolus vulgaris. Biochimica et Biophysica Acta, 374. pp. 187-196.

Book Section

Haeuptle, Marie-Theres ; Dobberstein, Bernhard (1986) Intracellular targeting and sorting of newly synthesized proteins. [Book Section]