Dissertation

Abazova, Nadeshda (2019) Dynamic Proteome Remodeling during Differentiation and Reprogramming. [Dissertation]

Adrian, Svenja (2019) FOXM1 and CKS1 - novel cellular targets of the HPV oncogenes. [Dissertation]

Bajak, Kathrin (2019) Networks of gene expression control in Trypanosoma brucei. [Dissertation]

Barile, Melania (2019) Mathematical modelling of the kinetic parameters of haematopoietic stem cells and their progeny. [Dissertation]

Ben Ayed, Sara (2019) Ca2+ signalling and its consequences in the mouse spinal cord dorsal horn under chronic pain. [Dissertation]

Bendinger, Alina Leandra (2019) Investigation of hypoxia in syngeneic rat prostate tumors after irradiation with photons or carbon ions by multimodal imaging and histology. [Dissertation]

Benjaminsen, Jørgen (2019) Investigating efficient apoptotic corps removal by microglia in the developing brain. [Dissertation]

Benk, Amelie Saskia (2019) Proteomics-based discovery of novel vascular accessible markers in kidney cancer. [Dissertation]

Best, Benedikt T. (2019) Rab-mediated membrane trafficking systems in terminal tracheal cells of Drosophila melanogaster. [Dissertation]

Bhide, Sourabh (2019) Co-ordination of cell shape changes during ventral furrow formation in Drosophila embryo. [Dissertation]

Blank-Giwojna, Alena (2019) Long non-coding RNA KHPS1 drives a regulatory cascade which activates expression of the protooncogene SPHK1. [Dissertation]

Bolbat, Andrey (2019) Genetically encoded FRET sensor to detect double-stranded RNA during viral infection. [Dissertation]

Boßler, Felicitas Martha (2019) AKT-dependent Repression of Human Papillomavirus E6/E7 Oncogene Expression under Hypoxia. [Dissertation]

Braun, Julia Alexandra (2019) The Effects of Iron Chelators on the Phenotype of HPV-Positive Cervical Cancer cells. [Dissertation]

Brosig, Sebastian (2019) Single Cell microRNA Dynamics during Mouse Embryonic Stem Cell Differentiation. [Dissertation]

Buczak, Katarzyzna (2019) Spatial proteomics: from tissue organization to protein function. [Dissertation]

Buhl, Juliane (2019) The senescence-associated secretory phenotype regulates the growth behavior of pediatric pilocytic astrocytoma. [Dissertation]

Bulli, Lorenzo (2019) The role of nuclear envelope associated proteins in early HIV 1 infection steps. [Dissertation]

Cazzola, Anna (2019) Identification and characterization of aneuploidy-selective compounds in acute myeloid leukemia. [Dissertation]

Chen, Chih-Yeh (2019) Induction of autoreactive regulatory T cells through promiscuous gene expression by bone marrow-resident plasma cells. [Dissertation]

Chowdhury, Artira (2019) Deciphering Interaction and Water Dynamics in Intrinsically Disordered Proteins with High Resolution Spectroscopic Tools. [Dissertation]

Christochowitz, Sandra (2019) Novel insights into the contribution of IL-13 to the pathogenesis of muco-obstructive lung disease. [Dissertation]

Cramer, Dina Silvia (2019) An interaction-based modeling approach to predict response to cancer drugs. [Dissertation]

Dang, Yonglong (2019) Post-transcriptional regulation of the transition from neural stem cells to early neuroblasts. [Dissertation]

Degen, Anna (2019) Exploring the use of a blue pigment-producing NRPS as a tagging method to easily detect engineered NRPs. [Dissertation]

Demirdizen, Engin (2019) Analysis of CENP-A loading and misincorporation in Drosophila melanogaster. [Dissertation]

Drucker, Elisabeth (2019) FUNCTIONAL AND MECHANISTIC CHARACTERIZATION OF THE NUCLEAR IMPORT RECEPTOR KARYOPHERIN-α2 IN LIVER CANCER. [Dissertation]

Dünnbier, Stefanie (2019) The role of Thioredoxin-interacting protein in T cell receptor signalling. [Dissertation]

Eisel, David (2019) Reprogramming of M2-like macrophages by CD4+ T cells, transcription factor knockdown and miRNA transfection. [Dissertation]

Eismann, Björn Benjamin (2019) Comparative assessment of induced abnormal mitotic events by high-throughput light sheet imaging and image analysis. [Dissertation]

Elzoheiry, Shehabeldin (2019) Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations. [Dissertation]

Ewen, Eva-Maria (2019) Pro-inflammatory cytokines unleash natural killer cell potential for tumor therapy : NK cells want to break free. [Dissertation]

Fakhiri, Julia (2019) With small viruses come giant responsibilities - Next-generation parvoviral vectors for human gene therapy with extended packaging capacity and enhanced safety profile. [Dissertation]

Falk, Henning Johannes (2019) Imaging the onset of the segmentation clock during mouse gastrulation. [Dissertation]

Fleming, Viktor (2019) Immunosuppression in malignant melanoma induced by tumor-derived extracellular vesicles. [Dissertation]

Florescu, Sebastian I. (2019) Ras Mapk Growth Effectors in Drosophila. [Dissertation]

Funck, Felix Lukas (2019) Innate immune cell crosstalk induces melanoma cell senescence. [Dissertation]

Förster, Laura-Christin (2019) Analysis of protein-sphingolipid interactions in Influenza A-infected cells. [Dissertation]

Gandhi, Minakshi (2019) Role of long non-coding RNA lincNMR in nucleotide metabolism in cancer. [Dissertation]

Gatzmann, Fanny (2019) DNA methylation in the marbled crayfish Procambarus virginalis. [Dissertation]

Goyal, Manu Jain (2019) Paralog specific role of COPI pathway in P19 neuronal differentiation. [Dissertation]

Granados Blanco, Karol Andrea (2019) Partial reprogramming - a model for melanoma targeted therapy resistance. [Dissertation]

Großeholz, Ruth (2019) Computational Modeling of the Fast Brassinosteroid Response in the Plasma Membrane of Arabidopsis thaliana: From Molecules to Organ. [Dissertation]

Hafermann, Juliane O. (2019) The effect of APOBEC3A-mediated mutagenesis on tumour growth of immortalised, transformed cells and on survival of head and neck squamous cell carcinoma patients. [Dissertation]

Hangel, Christoph (2019) Leptin-mediated downregulation of glutathione peroxidase 4 and iron overload contributing to podocyte ferroptosis in diabetic nephropathy. [Dissertation]

Hauke, Sebastian (2019) Investigations of Trace Amines and Fatty Acids as Essential Endogenous Signaling Factors for β-Cell Activity and Insulin Secretion. [Dissertation]

He, Feng (2019) Exploring the function of laccases from Miscanthus sinensis in lignin biosynthesis. [Dissertation]

Heidbüchel, Johannes Paul Walther (2019) Oncolytic measles viruses to support BiTE and CAR T cell re-direction immunotherapies of solid tumors. [Dissertation]

Hinsenkamp, Isabel (2019) The role of DLC1 in Helicobacter-related gastric disease. [Dissertation]

Holzwart, Eleonore (2019) The role of RLP44 in cell wall signalling integration and vascular cell fate determination in Arabidopsis thaliana. [Dissertation]

Hoppe, Stephanie (2019) Identification of target T cell epitopes for a therapeutic HPV16 vaccine. [Dissertation]

Imkeller, Katharina Christina (2019) Molecular characterization of public anti-PfCSP antibodies in human malaria. [Dissertation]

Iovino, Loredana (2019) Ultrastructural characterization of microtubules at high resolution in the mammalian peripheral nervous system. [Dissertation]

Jankowska-Döllken, Monika (2019) Functional studies on the chloroquine resistance transporter (PfCRT) and the HECT E3 ubiquitin-protein ligase (PfUT) in Plasmodium falciparum. [Dissertation]

Joshi, Swarnima (2019) Investigation of genes involved in muscle function using zebrafish. [Dissertation]

Kais, Britta (2019) Eignet sich der Fischembryotest als Werkzeug zur Bestimmung von spezifischer Toxizität in Embryonen des Zebrabärblings (Danio rerio)? [Dissertation]

Kalra, Priyata (2019) Integration of pharmacokinetic and intracellular models of interferon administration and induced responses. [Dissertation]

Kaspar, Sarah (2019) The role of promoter architecture in transduction, integration and multiplexing of environmental signals in bacteria. [Dissertation]

Kloss, Loreen (2019) Molecular and Functional Characterization of P2Y12 Expression in Tumor-associated Macrophages. [Dissertation]

Knaub, Maria (2019) Molecular downstream mechanisms of the oncogenic transcriptional regulators YAP/TAZ in hepatocarcinogenesis. [Dissertation]

Kreuter, Leon (2019) Bacteria in Public Swimming Pools – Inactivation Kinetics, Prevalence of Pathogens and Value of Indicators. [Dissertation]

Kruse, Sebastian (2019) Therapeutic vaccination against HPV-positive tumors in a MHC-humanized mouse model. [Dissertation]

Krüger, Daniel (2019) Regulation of Actomyosin Contraction during Tissue Morphogenesis: Genes and Mechanics. [Dissertation]

Kuchenov, Dmitry (2019) The sensing and processing of multiple extracellular cues by living cells. [Dissertation]

Kumberger, Peter Johannes Manuel Eduard (2019) Quantifying the Impact of Cell-to-Cell Transmission on Viral Spread. [Dissertation]

Kurilov, Roman (2019) Assessment of modeling strategies for drug response prediction in cell lines and xenografts. [Dissertation]

Kurth, Markus (2019) Probing the lipid environment of the G-protein coupled receptor Metabotropic glutamate receptor 2. [Dissertation]

Köhler, Florian (2019) Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome. [Dissertation]

Körber, Verena (2019) Somatic mutations and tissue turnover in glioblastoma and hematopoiesis. [Dissertation]

Lauer, Alexa Natalia (2019) A comparative transcriptome analysis of human and porcine choroid plexus cells in response to Streptococcus suis Serotype 2 infection. [Dissertation]

Liedgens, Linda (2019) Investigation of oxidative protein folding in protist mitochondria and elucidation of the catalytic mechanism of glutaredoxins. [Dissertation]

Lindner, Robert (2019) Blue-Light-Regulated Adenylyl Cyclases - optogenetic tools and model systems for inter-domain communication. [Dissertation]

Lischik, Colin (2019) Combining in vivo imaging and mechanistic approaches to investigate Wnt regulation of retinal stem cells. [Dissertation]

Lont, Sebastian Alexander (2019) Thrombozyten CD40-Ligand induzierte Endothelzellen-Monozyten Interaktion an Prädilektionsstellen für die Atherosklerose. [Dissertation]

Luque Molina, Inmaculada (2019) Extrinsic and Intrinsic Regulation of Adult Neural Stem Cell Activation. [Dissertation]

Martin-Garcia, Diego (2019) Characterization and modulation of CCR6/CCL20-mediated immunosurveillance in malignant melanoma. [Dissertation]

Marucha, Kevin (2019) The suppressive role of 4EIP and PUF3 in gene expression during differentiation of Trypanosoma brucei. [Dissertation]

Mederer, Tanja (2019) Identification and characterization of novel candidate genes for Hirschsprung's disease - a developmental disorder of the enteric nervous system. [Dissertation]

Moreau, Catherine A. (2019) Profilin in Plasmodium berghei gliding motility and development. [Dissertation]

Nass Kovacs, Gabriela (2019) Light-energy conversion in rhodopsins studied by time-resolved serial femtosecond crystallography. [Dissertation]

Nickl, Manuela (2019) Targeted cleavage of the HIV-1 genome in human cells using AAV-delivered CRISPR/Cas9. [Dissertation]

Nortmeyer, Maike Christine (2019) MYCN dependency of MYCN amplified neuroblastoma cell lines analyzed in relation to their interaction with BET proteins and in a novel orthotopic mouse model. [Dissertation]

Oberländer, Kristin (2019) Neuronal activity-dependent gene expression in learning and excitotoxicity. [Dissertation]

Pais Gomes Luís, Catarina (2019) Linking addiction-related behavior to synaptic efficacy and network activity in the prefrontal-accumbal pathway of behaving rats. [Dissertation]

Plum, Thomas (2019) Identification of lineage-specific marker for therapeutic targeting of mast cells. [Dissertation]

Radic Shechter, Ksenija (2019) Exploring the metabolic landscape and resulting vulnerabilities of minimal residual disease in breast cancer. [Dissertation]

Reinert, Janine Kristin (2019) Odour discrimination in mice with perturbed granule cells, assayed by automated behavioural testing. [Dissertation]

Remes, Anca (2019) Therapeutic transcription factor decoy oligodeoxynucleotides for Marfan syndrome and heart failure. [Dissertation]

Ridinger, Johannes (2019) HDAC10 in neuroblastoma chemoresistance. [Dissertation]

Rieger, Jan Hendrik (2019) Targets of tumor infiltrating lymphocyte reactivity in pancreatic cancer. [Dissertation]

Robador Arteta, Jose Ramon (2019) Crosstalk between melanoma cells and the blood-brain barrier: Impact on coagulation and brain metastasis to identify new anti-metastatic targets. [Dissertation]

Sander, Simone (2019) Relevance of ACSL3-mediated ACS activity and ACSL3 localization in anabolic and catabolic lipid droplet metabolism. [Dissertation]

Schmidt, Tobias Thomas (2019) Studies on DNA replication fidelity in Saccharomyces cerevisiae. [Dissertation]

Schneidt, Viktor (2019) Antibodies conjugated with viral antigens elicit a cytotoxic T cell response against primary CLL ex vivo. [Dissertation]

Schoch, Arne (2019) Quantitative Analysis of Information Transfer in Signal Transduction. [Dissertation]

Schwab, Melanie (2019) The Role of the Mucin-Like Glycoprotein Podoplanin in the Progression of Cutaneous Squamous Cell Carcinoma. [Dissertation]

Schürholz, Anne-Kathrin (2019) Spatio-temporal control of cell wall propterties and signalling networks in Arabidopsis meristems. [Dissertation]

Seleit, Ali (2019) On the Development and Evolution of the Lateral Line. [Dissertation]

Seyhan Agircan, Ayca (2019) Reflection confocal microscopy for the study of airway surface liquid dysregulation in cystic fibrosis. [Dissertation]

Sharma, Rakesh (2019) Understanding the role of Sphingosine 1-phosphate in regulating the microglia and glioma interactions. [Dissertation]

Sommerkamp, Pia (2019) Dissecting RNA biology in hematopoietic stem cells: The long non-coding RNA Meg3 is dispensable for hematopoiesis and alternative polyadenylation orchestrates hematopoietic stem cell function. [Dissertation]

Soni, Himanshu (2019) Deciphering Potential Role of Unfolded Protein Response in Glioblastoma. [Dissertation]

Sonntag, Hannah (2019) Elucidating astrocyte and neuron interactions using genetically encoded fluorescent indicators. [Dissertation]

Specht, Sandra (2019) Structure-function analysis and membrane association of Leishmania tarentolae and Plasmodium falciparum Erv. [Dissertation]

Spreng, Benjamin Roman (2019) The role of microtubules in Plasmodium berghei sporozoite development, morphology, motility and infectivity. [Dissertation]

Stapper, Zeenna A. (2019) The role of redox homeostasis in Drosophila models of Aß aggregation. [Dissertation]

Stäble, Sina (2019) Deconvolution of Hematopoietic Commitment Decisions by Genome-wide Analysis of Progressive DNA Methylation Changes. [Dissertation]

Tavhelidse, Tinatini (2019) The role of rx genes in establishment and maintenance of the medaka ciliary marginal zone. [Dissertation]

Toprak, Umut (2019) Integrative Analysis of Omics Datasets. [Dissertation]

Torkov, Alica (2019) Blinding the CYCLOPS - Neuroblastoma vulnerabilities unveiled by 1p loss. [Dissertation]

Trendel, Jakob (2019) Proteomic Exploration of Protein-RNA Interactions in Human Cells. [Dissertation]

Viswanathan, Ranjith (2019) Optogenetic modulation of Delta reveals the role of Notch signalling dynamics during tissue differentiation. [Dissertation]

Vodicska, Barbara (2019) Deciphering the function of MISP in mitotic spindle orientation. [Dissertation]

Vorländer, Matthias Kopano (2019) Structural studies of RNA Polymerase III transcription. [Dissertation]

Wagner, Claudius (2019) Role of matrix metalloproteinase-9 in cystic fibrosis lung disease and evaluation of therapeutic strategies. [Dissertation]

Wang, Bei-Tzu (2019) Characterization of ADP dependent glucokinase in the embryonic development of zebrafish. [Dissertation]

Wang, Jin (2019) Transcription factor Zas1: investigating its role in fission yeast. [Dissertation]

Wang, Zhongyi (2019) Ribosome profiling reveals principles of translatome and transcriptome evolution in mammalian organs. [Dissertation]

Weber, Rebecca (2019) Die Regulation der Glycodelin-Expression im Nicht-kleinzelligen Lungenkarzinom. [Dissertation]

Weigt, David (2019) Development of cellular metabolite-based MALDI mass spectrometry assays for drug discovery. [Dissertation]

Wutschka, Juliane (2019) Stromal loss of JUNB promotes distant metastasis. [Dissertation]

YANG, MI (2019) Applying machine learning to derive actionable insights in precision oncology. [Dissertation]

Youness, Berthe (2019) Molecular genetic analysis of functional FMR1/FMRP expression on human folliculogenesis and ovarian reserve. [Dissertation]

Zedan, Mostafa (2019) Analysis of the role of N-terminal acetylation of newly synthesized proteins in Saccharomyces cerevisiae. [Dissertation]

von Gerichten, Johanna (2019) Development of Mass Spectrometric Methods for Tissue Imaging and LC-based Quantification of Glycosphingolipids/Gangliosides including Tay-Sachs disease based Neuraminidase-deficient Mouse Models and Human Gut Microbiota. [Dissertation]

Öztürk, Mehmet Ali (2019) A computational approach to decipher chromatosome structure determinants. [Dissertation]