%0 Generic
%A Dovalil, Nina
%D 2010
%F heidok:11431
%K Kupfer(II) , Koordinationschemie , zyklische Peptide , ESR , PatellamideCopper(II) , Coordination Chemistry , cyclic peptides , EPR , patellamides
%R 10.11588/heidok.00011431
%T Copper(II) Coordination Chemistry of Cyclic Pseudo Hexa- and Octapeptides
%U https://archiv.ub.uni-heidelberg.de/volltextserver/11431/
%X Cyclic pseudo peptides that can be isolated from the marine genus lissoclinum (ascidians) exhibit an interesting and versatile copper(II) coordination chemistry. They are highly preorganized, well suited for the complexation of copper(II) and are found to preferably form dinuclear copper(II) complexes. The accumulation of copper(II) in the ascidians and its complexation in the ascidians by cyclic pseudo peptides suggests a metabolic role of the copper(II) complexes of these interesting molecules. Recent findings imply the involvement of dinuclear copper(II) complexes in capture and/or hydrolysis of atmospheric CO2. This thesis deals with the synthesis of the cyclic pseudo peptides H3L1, H4L4, H4L4-bn, H4Lrs, and H4LascA and with the investigation of the mono- and dinuclear copper(II) complexes of the cyclic pseudo hexa- and octapeptides H3L1-3, H3Lwa, H4L4, H4Lrs, H4Lox, and H4LascA and their potential as model systems for the natural macrocycles. The main focus is on the investigation of the dinuclear copper(II) complexes of cyclic pseudo octapeptides, their reaction with atmospheric CO2 to the corresponding carbonato bridged species, and the differences in coordination chemistry that arise from their different molecular structures (Chapter 4).