<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy"^^ . "The vast majority of proton therapy institutes employ passive scattering beamlines. Treatments are delivered by means of laterally and distally conformed homogeneous dose distributions for each beam direction by utilizing spread-out Bragg peaks and custom milled hardware. Most newly built proton facilities rely upon scanned proton beams to provide intensity modulated therapy (IMPT), improvements in treatment planning and delivery workflow. This thesis investigates the benefits of IMPT in fixed proton therapy beamlines and describes aspects of multileaf collimator (MLC) based IMPT delivery. We show that IMPT has the potential to increase the range of applications for fixed proton therapy beamlines. A method for sequencing intensity modulated treatment plans into a set of segments is presented and evaluated based on results obtained for a set of clinical situations. The resulting numbers of segments made delivery technically and logistically feasible. Neutron dose was found acceptable given a well optimized beamline. The dosimetric properties of one specific multileaf collimator were investigated experimentally and compared to custom milled apertures. Small differences were found, but those are clinically insignificant in the vast majority of clinical cases. Finally, an extensive set of measurements for accurate determination of the peak dose as a function of field size is described."^^ . "2011" . . . . . . . . "Juliane"^^ . "Daartz"^^ . "Juliane Daartz"^^ . . . . . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy (PDF)"^^ . . . "2011_03_03_JD_PHD_THESIS.pdf"^^ . . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Opportunities and limitations of multileaf collimator based intensity modulated proton therapy (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #12077 \n\nOpportunities and limitations of multileaf collimator based intensity modulated proton therapy\n\n" . "text/html" . . . "530 Physik"@de . "530 Physics"@en . .