TY  - GEN
A1  - Wagner, Jennifer
UR  - https://archiv.ub.uni-heidelberg.de/volltextserver/12602/
N2  - This work establishes quality control for selective deposition of tribo-electrically charged micro-particles containing pre-activated amino acids onto a CMOS-chip in order to achieve high peptide densities in a modified Merrifield peptide synthesis. It encompasses the setup and implementation of an image processing supported auto- mated assessment of the particle depositions based on the analysis of the particles used, modelling the particle transfer out of an aerosol, deducing optimised param- eters and finding a surface analysis experiment that allows for semi-quantitative spatially resolved detection of amino acids coupled to the support in the microm- eter range. Furthermore, a flexible stand-alone interface to the control program of the automated system is implemented.
TI  - Quality control for peptide chip array production
KW  - quality control 
KW  -  peptide synthesis 
KW  -  image processing 
KW  -  surface analysis
Y1  - 2011///
ID  - heidok12602
AV  - public
ER  -