title: Development of a Pencil Beam Algorithm for the fast Calculation of Dose applied in keV Imaging Procedures in Image Guided Radiotherapy
creator: Jetter, Siri
subject: ddc-530
subject: 530 Physics
description: Over the last years, the introduction of image guided radiotherapy into clinical practice has led to an increased exposure of patients to radiation in keV imaging procedures. Daily imaging can signi cantly contribute to the dose in the organs at risk. The accurate assessment of this additional dose due to imaging is essential for the inclusion of the dose into the therapy planning process. In this work, the development of a fast patient speci c dose calculation algorithm for the keV energy range is presented. The algorithm is based on a pencil beam algorithm combined with semi-empirical factors for the scaling of depth and dose to account for inhomogeneities. To achieve a high accuracy, a high number of di erent body tissues is included in the design of the algorithm as well as in the Monte Carlo simulation used as the gold standard. The accuracy and limitations of the algorithm are evaluated for di erent phantom and patient geometries. For the application to patients, the proposed algorithm is shown to accurately calculate the mean dose in organs at risk for all beam geometries and accurate dose distributions for the full patient geometries for cone beam CT acquisitions within a very short timeframe.
date: 2011
type: Dissertation
type: info:eu-repo/semantics/doctoralThesis
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserver/12660/1/Dissertation_sjetter_600ppi.pdf
identifier: DOI:10.11588/heidok.00012660
identifier: urn:nbn:de:bsz:16-opus-126609
identifier:   Jetter, Siri  (2011) Development of a Pencil Beam Algorithm for the fast Calculation of Dose applied in keV Imaging Procedures in Image Guided Radiotherapy.  [Dissertation]     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/12660/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng