<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Realizing a new paradigm in radiation therapy treatment planning"^^ . "This thesis investigates the feasibility of a new IMRT planning paradigm called Interactive Dose Shaping (IDS).\r\nThe IDS paradigm enables the therapist to directly impose local dose features into the therapy plan. In contrast\r\nto the conventional IMRT planning approach, IDS does not employ an objective function to drive an iterative\r\noptimization procedure.\r\nIn the first part of this work, the conventional IMRT plan optimization method is investigated. Concepts for a\r\nnear-optimal implementation of the planning problem are provided. The second part of this work introduces the\r\nIDS concept. It is designed to overcome clinical drawbacks of the conventional method on the one hand and to\r\nprovide interactive planning strategies which exploit the full potential of modern high-performance computer\r\nhardware on the other hand. The realization of the IDS concept consists of three main parts. (1)A two-step Dose\r\nVariation and Recovery (DVR) strategy which imposes localized plan features and recovers for unintentional\r\nplan modifications elsewhere. (2)A new dose calculation method (3)The design of an IDS planning framework\r\nwhich provides a powerful graphical user interface.\r\nIt could be shown that the IDS paradigm is able to reproduce conventionally optimized therapy plans and\r\nthat the IDS concepts can be realized in real-time."^^ . "2013" . . . . . . . "Peter"^^ . "Ziegenhein"^^ . "Peter Ziegenhein"^^ . . . . . . "Realizing a new paradigm in radiation therapy treatment planning (PDF)"^^ . . . "diss_ziegenhein.pdf"^^ . . . "Realizing a new paradigm in radiation therapy treatment planning (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Realizing a new paradigm in radiation therapy treatment planning (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Realizing a new paradigm in radiation therapy treatment planning (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Realizing a new paradigm in radiation therapy treatment planning (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Realizing a new paradigm in radiation therapy treatment planning (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #15403 \n\nRealizing a new paradigm in radiation therapy treatment planning\n\n" . "text/html" . . . "004 Informatik"@de . "004 Data processing Computer science"@en . . . "530 Physik"@de . "530 Physics"@en . . . "570 Biowissenschaften, Biologie"@de . "570 Life sciences"@en . .