eprintid: 17817
rev_number: 27
eprint_status: archive
userid: 1329
dir: disk0/00/01/78/17
datestamp: 2014-12-16 13:34:48
lastmod: 2015-07-25 11:29:19
status_changed: 2014-12-17 12:19:25
type: article
metadata_visibility: show
creators_name: Bellemann, Nadine
creators_name: Stampfl, Ulrike
creators_name: Sommer, Christof M.
creators_name: Kauczor, Hans-Ulrich
creators_name: Schemmer, Peter
creators_name: Radeleff, Boris A.
title: Portal vein embolization using a Histoacryl/Lipiodol mixture before right liver resection
subjects: ddc-610
divisions: i-910200
divisions: i-911400
abstract: Purpose: The purpose of this retrospective study was to evaluate the efficacy and safety of percutaneous transhepatic portal vein embolization (PVE) of the right liver lobe using Histoacryl/Lipiodol mixture to induce contralateral liver hypertrophy before right-sided (or extended right-sided) hepatectomy in patients with primarily unresectable liver tumors. Methods: Twenty-one patients (9 females and 12 males) underwent PVE due to an insufficient future liver remnant; 17 showed liver metastases and 4 suffered from biliary cancer. Imaging was performed prior to and 4 weeks after PVE. Surgery was scheduled for 1 week after a CT or MRI control. The primary study end point was technical success, defined as complete angiographical occlusion of the portal vein. The secondary study end point was evaluation of liver hypertrophy by CT and MRI volumetry and transfer to operability. Results: In all the patients, PVE could be performed with a with a Histoacryl/Lipiodol mixture (n = 20) or a Histoacryl/
Lipiodol mixture with microcoils (n = 1). No procedure-related complications occurred. The volume of the left liver lobe increased significantly (p < 0.0001) by 28% from a mean of 549 ml to 709 ml. Eighteen of twenty-one patients (85.7%) could be transferred to surgery, and the intended resection could be performed as planned in 13/18 (72.3%) patients. Conclusion: Preoperative right-sided PVE using a Histoacryl/Lipiodol mixture is a safe technique and achieves a sufficient hypertrophy of the future liver remnant in the left liver lobe.
date: 2012
publisher: S. Karger AG
id_scheme: DOI
id_number: 10.11588/heidok.00017817
ppn_swb: 1653748877
own_urn: urn:nbn:de:bsz:16-heidok-178177
language: eng
bibsort: BELLEMANNNPORTALVEIN2012
full_text_status: public
publication: Digestive surgery
volume: 29
number: 3
pagerange: 236-242
issn: 0253-4886
citation:   Bellemann, Nadine ; Stampfl, Ulrike ; Sommer, Christof M. ; Kauczor, Hans-Ulrich ; Schemmer, Peter ; Radeleff, Boris A.  (2012) Portal vein embolization using a Histoacryl/Lipiodol mixture before right liver resection.  Digestive surgery, 29 (3).  pp. 236-242.  ISSN 0253-4886     
document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/17817/1/DSU2012029003236.pdf