%0 Journal Article
%@ 1468-6694
%A Wilder-Smith, Annelies
%A Byass, Peter
%A Olanratmanee, Phanthip
%A Maskhao, Pongsri
%A Sringernyuang, Luechai
%A Logan, James G.
%A Lindsay, Steve W.
%A Banks, Sarah
%A Gubler, Duane
%A Louis, Valérie R.
%A Tozan, Yesim
%A Kittayapong, Pattamaporn
%C London
%D 2012
%F heidok:18653
%I BioMed Central
%J Trials
%N 212
%P 1-7
%T The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand
%U https://archiv.ub.uni-heidelberg.de/volltextserver/18653/
%V 13
%X There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. Methods: A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7–18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. Discussion: Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. Trial registration clinicaltrial.gov. Registration number: NCT01563640