eprintid: 19343 rev_number: 31 eprint_status: archive userid: 1589 dir: disk0/00/01/93/43 datestamp: 2015-11-24 12:19:42 lastmod: 2024-05-24 12:51:52 status_changed: 2015-11-24 12:19:42 type: article metadata_visibility: show creators_name: Roggenbach, Jens creators_name: Saur, Patrick creators_name: Hofer, Stefan creators_name: Bruckner, Thomas creators_name: Preusch, Michael creators_name: Carbone, Remo creators_name: Walther, Andreas title: Incidence of perioperative sleep-disordered breathing in patients undergoing major surgery: a prospective cohort study subjects: ddc-610 divisions: i-910100 divisions: i-910300 divisions: i-911800 abstract: Background: Major surgery might have a modulating effect on nocturnal breathing patterns. The incidence and course of perioperative sleep-disordered breathing in individuals without a previous diagnosis of obstructive sleep apnea has not been investigated sufficiently so far. Methods: In this study, polygraphic recordings have been obtained from 37 inpatients without a diagnosis of obstructive sleep apnea syndrome during the preoperative night before and six nights following major surgical procedures. Eligible patients consenting to participate in this study underwent polygraphic recordings including four items (O2-saturation, pulse, nasal air flow and snoring) during the study period. Polygraphic data obtained from the postoperative recordings were compared to preoperative recordings. Results: Median (IQR [range]) apnea-hypopnea-index (AHI) for the whole group was 6,0 (2,5 - 14,7 [0–32,6]) in the preoperative night and increased in the following six nights post surgery: second night: 5,6 (2,6-15,0 [1,1 - 59,3]); third night: 16,9 (5,6 - 38,8 [2,9 - 64,3]); fourth night: 11,6 (5,9 - 17,3 [0,4 - 39,3]); fifth night: 15,2 (5,7 - 22,2 [0,2 - 55,5]); sixth night: 22,5 (5,2 - 35,4 [0,2 - 67,7]). AHI-scores of the third to sixth night post surgery differed significantly from data observed in the preoperative night. Conclusion: A significant increase in the AHI occurred frequently after major surgical procedures in the late postoperative period. Sleep-disordered breathings in the late postoperative period deserve attention, as they potentially increase the risk of postoperative complications. date: 2014 publisher: BioMed Central id_scheme: DOI ppn_swb: 165370005X own_urn: urn:nbn:de:bsz:16-heidok-193433 language: eng bibsort: ROGGENBACHINCIDENCEO2014 full_text_status: public publication: Patient safety in surgery volume: 8 number: 13 place_of_pub: London pagerange: 1-5 issn: 1754-9493 citation: Roggenbach, Jens ; Saur, Patrick ; Hofer, Stefan ; Bruckner, Thomas ; Preusch, Michael ; Carbone, Remo ; Walther, Andreas (2014) Incidence of perioperative sleep-disordered breathing in patients undergoing major surgery: a prospective cohort study. Patient safety in surgery, 8 (13). pp. 1-5. ISSN 1754-9493 document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/19343/1/13037_2013_Article_223.pdf