<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial"^^ . "Background: Stereotactic body radiation therapy (SBRT)using intensity-modulated radiotherapy (IMRT) can be a safe modality for treating spinal bone metastasis with enhanced targeting accuracy and an effective method for achieving good tumor control and a rigorous pain response. Methods/design: This is a single-center, prospective randomized controlled trial to evaluate pain relief after RT and consists of two treatment groups with 30 patients in each group. One group will receive single-fraction intensity-modulated RT with 1×24 Gy, and the other will receive fractionated RT with 10×3 Gy. The target parameters will be measured at baseline and at 3 and 6 months after RT. Discussion: The aim of this study is to evaluate pain relief after RT in patients with spinal bone metastases by means of two different techniques: stereotactic body radiation therapy and fractionated RT. The primary endpoint is pain relief at the 3-month time-point after RT. Secondly, quality of life, fatigue, overall and bone survival, and local control will be assessed. Trial registration ClinicalTrials.gov identifier NCT02358720 (June 2, 2015). "^^ . "2015" . . "16" . "264" . . "BioMed Central"^^ . . . "Trials"^^ . . . "14686694" . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "Sonja"^^ . "Katayama"^^ . "Sonja Katayama"^^ . . "Stefan"^^ . "Rieken"^^ . "Stefan Rieken"^^ . . "Jürgen"^^ . "Debus"^^ . "Jürgen Debus"^^ . . "Tilman"^^ . "Bostel"^^ . "Tilman Bostel"^^ . . "Harald"^^ . "Rief"^^ . "Harald Rief"^^ . . "Robert"^^ . "Wolf"^^ . "Robert Wolf"^^ . . "Florian"^^ . "Sterzing"^^ . "Florian Sterzing"^^ . . "Ingmar"^^ . "Schlampp"^^ . "Ingmar Schlampp"^^ . . "Thomas"^^ . "Bruckner"^^ . "Thomas Bruckner"^^ . . "Robert"^^ . "Förster"^^ . "Robert Förster"^^ . . . . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial (PDF)"^^ . . . "13063_2015_Article_761.pdf"^^ . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial (Other)"^^ . . . . . . "preview.jpg"^^ . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial (Other)"^^ . . . . . . "medium.jpg"^^ . . . "High-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #19405 \n\nHigh-dose single-fraction IMRT versus fractionated external beam radiotherapy for patients with spinal bone metastases: study protocol for a randomized controlled trial\n\n" . "text/html" . . . "610 Medizin"@de . "610 Medical sciences Medicine"@en . .