title: Resection of thoracic malignancies infiltrating cardiac structures with use of cardiopulmonary bypass
creator: Arif, Rawa
creator: Eichhorn, Florian
creator: Kallenbach, Klaus
creator: Seppelt, Philipp
creator: Ruhparwar, Arjang
creator: Dienemann, Hendrik
creator: Karck, Matthias
subject: 610
subject: 610 Medical sciences Medicine
description: Background: Only few reports exist on malignant thoracic neoplasms that require cardiopulmonary bypass during resection. We aimed to investigate the early and late clinical outcome of these patients.   Methods: Patients with thoracic malignancies that underwent surgery between 2002 and 2014 were analyzed. All patients had cardiopulomonary bypass support during resection. Clinical and perioperative data was retrospectively reviewed for outcome and overall survival.   Results: Fifteen patients (12 female, mean age of 55 ± 15 years, range 24 to 80 years) were identified. Eleven (8 female) were diagnosed with primary thoracic malignomas and four with metastases. Three patients died early postoperatively. Patients diagnosed with sarcoma had a significantly worse outcome than non-sarcoma patients (83.3 ± 15.2 % after 1 year, 31.3 ± 24.5 % after 5 years vs. 83.3 ± 15.2 % after 1 year, 0 ± 0 % after 5 years, p = 0.005).   Conclusions: Malignancies with extension into cardiac structures or infiltration of great vessels can be resected with cardiopulmonary bypass support and tolerable risk. Carefully selected patients can undergo advanced operative procedures with an acceptable 1-year-survival, but only few patients achieved good long-term outcome.  
publisher: BioMed Central
date: 2015
type: Article
type: info:eu-repo/semantics/article
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/19481/1/13019_2015_Article_296.pdf
identifier: DOI:
identifier: urn:nbn:de:bsz:16-heidok-194815
identifier:   Arif, Rawa ; Eichhorn, Florian ; Kallenbach, Klaus ; Seppelt, Philipp ; Ruhparwar, Arjang ; Dienemann, Hendrik ; Karck, Matthias  (2015) Resection of thoracic malignancies infiltrating cardiac structures with use of cardiopulmonary bypass.  Journal of Cardiothoracic Surgery, 10 (87).  pp. 1-8.  ISSN 1749-8090     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/19481/
rights: info:eu-repo/semantics/openAccess
rights: Please see front page of the work (Sorry, Dublin Core plugin does not recognise license id)
language: eng