<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing"^^ . "The aim of this work is to develop a compressed sensing (CS) based optimization for in- verse treatment planning in radiation therapy. This approach is applied to the example of brachytherapy where fast optimization is essential during intra-operative treatment planning.\r\nIn this thesis, a novel approach is presented that allows real-time intra-operative plan- ning for the first time. The standard inverse treatment problem is reformulated to resemble a CS problem. Highly specific solvers are developed and incorporated into a novel treatment planning system. By incorporating biological models and clinically important dosimetric criteria, the objective functions become more realistic.\r\nBeing approximately two orders of magnitude faster than state-of-the-art methods, the CS based approach is proven to return the same or better quality in plans. The inherit sparsity approach in CS allows to decrease the amount of needles by up to 25% reducing the intervention time and the probability of side effects. In addition, the new objective functions further simplify the treatment planning.\r\nThe novel CS based strategy and solvers can also be applied to other modalities in radi- ation therapy, e.g. intensity-modulated radiation therapy. The incorporation of sparse solution is a novel and promising paradigm for optimization in medical physics."^^ . "2015" . . . . . . . "Christian Vinzenz"^^ . "Guthier"^^ . "Christian Vinzenz Guthier"^^ . . . . . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing (PDF)"^^ . . . "Dissertation_pdfa.pdf"^^ . . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Development of a real-time inverse planning system for radiation therapy based on compressed sensing (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #19781 \n\nDevelopment of a real-time inverse planning system for radiation therapy based on compressed sensing\n\n" . "text/html" . . . "530 Physik"@de . "530 Physics"@en . . . "610 Medizin"@de . "610 Medical sciences Medicine"@en . .