TY  - JOUR
Y1  - 2013///
TI  - The history of neuromyelitis optica
SP  - 1
EP  - 12
JF  - Journal of Neuroinflammation
A1  - Jarius, Sven
A1  - Wildemann, Brigitte
SN  - 1742-2094
CY  - London
VL  - 10
IS  - 8
PB  - BioMed Central
UR  - https://archiv.ub.uni-heidelberg.de/volltextserver/20113/
AV  - public
ID  - heidok20113
N2  - The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO). While the history of classical multiple sclerosis has been extensively studied, only little is known about the history of NMO. In the present article, we provide a comprehensive review of the early history of this rare but intriguing syndrome. We trace the origins of the concept of NMO in the 19th century medical literature and follow its evolution throughout the 20th and into the 21st century. Finally, we discuss recent proposals to revise the concept of NMO and explain why there is indeed a need for a more systematic and descriptive nomenclature.
ER  -