eprintid: 20113
rev_number: 14
eprint_status: archive
userid: 1589
dir: disk0/00/02/01/13
datestamp: 2016-02-17 10:47:38
lastmod: 2024-03-10 22:17:52
status_changed: 2016-02-17 10:47:38
type: article
metadata_visibility: show
creators_name: Jarius, Sven
creators_name: Wildemann, Brigitte
title: The history of neuromyelitis optica
subjects: 610
divisions: 712000
divisions: 911100
abstract: The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO). While the history of classical multiple sclerosis has been extensively studied, only little is known about the history of NMO. In the present article, we provide a comprehensive review of the early history of this rare but intriguing syndrome. We trace the origins of the concept of NMO in the 19th century medical literature and follow its evolution throughout the 20th and into the 21st century. Finally, we discuss recent proposals to revise the concept of NMO and explain why there is indeed a need for a more systematic and descriptive nomenclature.
date: 2013
publisher: BioMed Central
id_scheme: DOI
ppn_swb: 1657160750
own_urn: urn:nbn:de:bsz:16-heidok-201138
language: eng
bibsort: JARIUSSVENTHEHISTORY2013
full_text_status: public
publication: Journal of Neuroinflammation
volume: 10
number: 8
place_of_pub: London
pagerange: 1-12
issn: 1742-2094
citation:   Jarius, Sven ; Wildemann, Brigitte  (2013) The history of neuromyelitis optica.  Journal of Neuroinflammation, 10 (8).  pp. 1-12.  ISSN 1742-2094     
document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/20113/1/12974_2012_Article_797.pdf