title: One life ends, another begins: Management of a brain-dead pregnant mother - A systematic review -
creator: Esmaeilzadeh, Majid
creator: Dictus, Christine
creator: Kayvanpour, Elham
creator: Sedaghat-Hamedani, Farbod
creator: Eichbaum, Michael
creator: Hofer, Stefan
creator: Engelmann, Guido
creator: Fonouni, Hamidreza
creator: Golriz, Mohammad
creator: Schmidt, Jan
creator: Unterberg, Andreas
creator: Mehrabi, Arianeb
creator: Ahmadi, Rezvan
subject: 610
subject: 610 Medical sciences Medicine
description: Background: An accident or a catastrophic disease may occasionally lead to brain death (BD) during pregnancy. Management of brain-dead pregnant patients needs to follow special strategies to support the mother in a way that she can deliver a viable and healthy child and, whenever possible, also be an organ donor. This review discusses the management of brain-dead mothers and gives an overview of recommendations concerning the organ supporting therapy.   Methods: To obtain information on brain-dead pregnant women, we performed a systematic review of Medline, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL). The collected data included the age of the mother, the cause of brain death, maternal medical complications, gestational age at BD, duration of extended life support, gestational age at delivery, indication of delivery, neonatal outcome, organ donation of the mothers and patient and graft outcome.   Results: In our search of the literature, we found 30 cases reported between1982 and 2010. A nontraumatic brain injury was the cause of BD in 26 of 30 mothers. The maternal mean age at the time of BD was 26.5 years. The mean gestational age at the time of BD and the mean gestational age at delivery were 22 and 29.5 weeks, respectively. Twelve viable infants were born and survived the neonatal period.   Conclusion: The management of a brain-dead pregnant woman requires a multidisciplinary team which should follow available standards, guidelines and recommendations both for a nontraumatic therapy of the fetus and for an organ-preserving treatment of the potential donor.
publisher: BioMed Central; Springer
date: 2010
type: Article
type: info:eu-repo/semantics/article
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/21587/1/12916_2010_Article_333.pdf
identifier: DOI:http://dx.doi.org/10.1186/1741-7015-8-74
identifier: urn:nbn:de:bsz:16-heidok-215872
identifier:   Esmaeilzadeh, Majid ; Dictus, Christine ; Kayvanpour, Elham ; Sedaghat-Hamedani, Farbod ; Eichbaum, Michael ; Hofer, Stefan ; Engelmann, Guido ; Fonouni, Hamidreza ; Golriz, Mohammad ; Schmidt, Jan ; Unterberg, Andreas ; Mehrabi, Arianeb ; Ahmadi, Rezvan  (2010) One life ends, another begins: Management of a brain-dead pregnant mother - A systematic review -.  BMC Medicine, 8 (74).  pp. 1-11.  ISSN 1741-7015     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/21587/
rights: info:eu-repo/semantics/openAccess
rights: Please see front page of the work (Sorry, Dublin Core plugin does not recognise license id)
language: eng