<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients"^^ . "Background: The distinction between right-sided and left-sided colon cancer has recently received considerable attention due to differences regarding underlying genetic mutations. There is an ongoing debate if right- versus left-sided tumor location itself represents an independent prognostic factor. We aimed to investigate this question by using propensity score matching. Methods: Patients with resected, stage I - III colon cancer were identified from the Surveillance, Epidemiology, and End Results (SEER) database (2004–2012). Both univariable and multivariable Cox regression as well as propensity score matching were used. Results: Overall, 91,416 patients (51,937 [56.8%] with right-sided, 39,479 [43.2%] with left-sided colon cancer; median follow-up 38 months) were eligible. In univariable analysis, patients with right-sided cancer had worse overall (hazard ratio [HR] = 1.32, 95% CI:1.29–1.36, P < 0.001) and cancer-specific survival (HR = 1.26, 95% CI:1.21–1.30, P < 0.001) compared to patients with left-sided cancer. After propensity score matching, the prognosis of right-sided carcinomas was better regarding overall (HR = 0.92, 95% CI: 0.89 − 0.94, P < 0.001) and cancer-specific survival (HR = 0.90, 95% CI:0.87 − 0.93, P < 0.001). In stage I and II, the prognosis of right-sided cancer was better for overall (HR = 0.89, 95% CI:0.84–0.94 and HR = 0.85, 95% CI:0.81–0.89) and cancer-specific survival (HR = 0.71, 95% CI:0.64 − 0.79 and HR = 0.75, 95% CI:0.70–0.80). Right- and left-sided colon cancer had a similar prognosis for stage III (overall: HR = 0.99, 95% CI:0.95–1.03 and cancer-specific: HR = 1.04, 95% CI:0.99–1.09). Conclusions: This population-based analysis on stage I - III colon cancer provides evidence that the prognosis of localized right-sided colon cancer is better compared to left-sided colon cancer. This questions the paradigm from previous research claiming a worse survival in right-sided colon cancer patients."^^ . "2016" . . "16" . "554" . . "BioMed Central; Springer"^^ . . . "BMC Cancer"^^ . . . "14712407" . . . . . . . . . . . . . . . . . . . . . . . "Lukas"^^ . "Marti"^^ . "Lukas Marti"^^ . . "Michael C."^^ . "Sulz"^^ . "Michael C. Sulz"^^ . . "Ulrich"^^ . "Güller"^^ . "Ulrich Güller"^^ . . "Ignazio"^^ . "Tarantino"^^ . "Ignazio Tarantino"^^ . . "Thomas"^^ . "Cerny"^^ . "Thomas Cerny"^^ . . "Rene"^^ . "Warschkow"^^ . "Rene Warschkow"^^ . . "Bruno M."^^ . "Schmied"^^ . "Bruno M. Schmied"^^ . . . . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients (PDF)"^^ . . . "12885_2016_Article_2412.pdf"^^ . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients (Other)"^^ . . . . . . "small.jpg"^^ . . . "Better survival in right-sided versus left-sided stage I - III colon cancer patients (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #21656 \n\nBetter survival in right-sided versus left-sided stage I - III colon cancer patients\n\n" . "text/html" . . . "610 Medizin"@de . "610 Medical sciences Medicine"@en . .