title: Development of highly integrated PET/MR detector modules
creator: Sacco, Ilaria
subject: 530
subject: 530 Physics
subject: 600
subject: 600 Technology (Applied sciences)
description: In the last 20 years, PET imaging has become a very valuable technique for clinical diagnosis. It gives functional information on glucose metabolism and  cancerous cell growth and, if coupled with precise anatomical information from MRT scans, can lead to very accurate results. The aim of the present work is the design of highly performing PET detector modules, to be used for both clinical and pre-clinical applications and compatible with operations inside MR scanner. A single-layer ceramic module, hosting both sensors and readout electronics, efficiently thermally decoupled thanks to an integrated liquid cooling channel, has been designed, fabricated  and tested. Novel single-ended front-end architecture, studied for low input impedance and good timing resolution, has been designed and integrated on PETA ASIC for SiPM readout. SiPM dies for maximum light collection and  identification of sub-millimeter scintillating crystals have been designed and characterized. The assembly is very compact, with an area of 32mm x 32mm, about 8mm thick without crystals, with up to 144 readout channels. It has  proved excellent ToF resolution of about 230 ps CRT at FWHM for detectors in coincidence. The same module has been able to identify sub-millimeter scintillating crystals.
date: 2016
type: Dissertation
type: info:eu-repo/semantics/doctoralThesis
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/22239/1/main.pdf
identifier: DOI:10.11588/heidok.00022239
identifier: urn:nbn:de:bsz:16-heidok-222391
identifier:   Sacco, Ilaria  (2016) Development of highly integrated PET/MR detector modules.  [Dissertation]     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/22239/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng