<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy"^^ . "Helium and carbon ions enable a more conformal dose distribution, narrower penumbra\r\nand higher relative biological effectiveness than photon and proton radiotherapy.\r\nHowever, they may undergo nuclear fragmentation in the patient tissues and the arising\r\nsecondary fragments affect the delivered biological dose distributions. Currently there\r\nis a lack of data regarding ion nuclear fragmentation. One reason is the large size (up to\r\nsome meters) of the experimental setups required for the investigations. In this thesis a\r\nnew method is presented, which makes use of versatile pixelated semiconductor detectors\r\n(Timepix). This method is based on tracking of single particles and pattern recognition\r\nof their signals in the detectors.\r\nMeasurements were performed at the HIT facility. The mixed radiation field arising\r\nfrom 430 MeV/u carbon ion beams and 221 MeV/u helium ion beams in water and in\r\nPMMA targets was investigated. The amounts of primary (carbon or helium) ions detected\r\nbehind targets with the same water equivalent thickness (WET) were found to be\r\nin agreement within the statistical uncertainties. However, more fragments (differences\r\nup to 20% in case of H) and narrower lateral particle distributions were measured behind\r\nthe PMMA than the water targets.\r\nThe spectra of ions behind tissue surrogates and corresponding water targets with the\r\nsame WET were analysed. The results obtained with adipose and inner bone surrogates\r\nand with the equivalent water phantoms were found to be consistent within the\r\nuncertainties. Significant differences in the results were observed in the case of lung and\r\ncortical bone surrogates when compared to the water phantoms.\r\nThe experimental results were compared to FLUKA Monte Carlo simulations. This comparison\r\ncould contribute to enhance the ion interaction models currently implemented\r\nfor 12C and 4He ion beams."^^ . "2016" . . . . . . . "Giulia"^^ . "Aricó"^^ . "Giulia Aricó"^^ . . . . . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy (PDF)"^^ . . . "AricoGiulia_PhD_Dissertation_2016.pdf"^^ . . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Ion Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #22292 \n\nIon Spectroscopy for improvement of the Physical Beam Model for Therapy Planning in Ion Beam Therapy\n\n" . "text/html" . . . "530 Physik"@de . "530 Physics"@en . . . "600 Technik, Medizin, angewandte Wissenschaften"@de . "600 Technology (Applied sciences)"@en . .