title: Synthesis and evaluation of novel picolinic acid-based bispidine ligands and their metal complexes for the application in nuclear medicine creator: Rück, Katharina subject: ddc-500 subject: 500 Natural sciences and mathematics subject: ddc-540 subject: 540 Chemistry and allied sciences description: Defeating cancer is one of the major challenges that humankind is facing today. To this end, nuclear medicine offers promising approaches including radiometal-based pharmaceuticals. The work presented in this thesis focused on the development of new ligand systems for application as metal-chelating units in radiopharmaceuticals. These novel ligands were evaluated in various non-radioactive and radioactive metal complexation studies concerning their potential application in nuclear medicine. date: 2017 type: Dissertation type: info:eu-repo/semantics/doctoralThesis type: NonPeerReviewed format: application/pdf identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/23257/1/Dissertation_Rueck_A-1b.pdf identifier: DOI:10.11588/heidok.00023257 identifier: urn:nbn:de:bsz:16-heidok-232576 identifier: Rück, Katharina (2017) Synthesis and evaluation of novel picolinic acid-based bispidine ligands and their metal complexes for the application in nuclear medicine. [Dissertation] relation: https://archiv.ub.uni-heidelberg.de/volltextserver/23257/ rights: info:eu-repo/semantics/openAccess rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html language: eng