%0 Generic
%A Rück, Katharina
%D 2017
%F heidok:23257
%K Ligand synthesis, Coordination chemistry, Nuclear medicine
%R 10.11588/heidok.00023257
%T Synthesis and evaluation of novel picolinic acid-based bispidine ligands and their metal complexes for the application in nuclear medicine
%U https://archiv.ub.uni-heidelberg.de/volltextserver/23257/
%X Defeating cancer is one of the major challenges that humankind is facing today. To this end, nuclear medicine offers promising approaches including radiometal-based pharmaceuticals. The work presented in this thesis focused on the development of new ligand systems for application as metal-chelating units in radiopharmaceuticals. These novel ligands were evaluated in various non-radioactive and radioactive metal complexation studies concerning their potential application in nuclear medicine.