eprintid: 24050 rev_number: 18 eprint_status: archive userid: 3571 dir: disk0/00/02/40/50 datestamp: 2018-02-12 07:41:18 lastmod: 2018-03-01 14:06:58 status_changed: 2018-02-12 07:41:18 type: doctoralThesis metadata_visibility: show creators_name: Spindeldreier, Claudia Katharina title: Dosimetry with ionization chambers and optically stimulated luminescence detectors in magnetic fields subjects: ddc-530 divisions: i-130001 adv_faculty: af-13 abstract: Hybrid magnetic resonance guided radiotherapy (MRgRT) devices allow imaging the patient during treatment by means of non-ionizing radio-frequency. This technology enables real-time image guided radiotherapy, thereby it is expected to improve treatment precision and clinical outcome. In order to use hybrid MRgRT devices clinically, dosimetry needs to be performed in the static magnetic field of the magnetic resonance imaging scanner for commissioning and quality assurance measurements. For this purpose, the applicability of two detector types - ionization chambers and optically stimulated luminescence detectors (OSLDs) - for dosimetry in magnetic fields was investigated in this work by means of experimental measurements and Monte Carlo simulations. The ionization chambers show a response that depends on the magnetic field strength and orientation as well as on the sensitive chamber volume. Likewise, the effective point of measurement is influenced by these parameters. In order to account for these effects, magnetic field correction factors were calculated. Also the response of OSLDs was found to depend on the magnetic field strength and direction. No substantial change in their angular dependence due to the magnetic field could be measured. In conclusion, both detector types can be used for precise dosimetry in high magnetic fields when applying the calculated magnetic field correction factors or when calibrating the detectors directly in the magnetic field. date: 2018 id_scheme: DOI id_number: 10.11588/heidok.00024050 ppn_swb: 1653248912 own_urn: urn:nbn:de:bsz:16-heidok-240500 date_accepted: 2018-01-26 advisor: HASH(0x55a718445820) language: eng bibsort: SPINDELDREDOSIMETRYW2018 full_text_status: public citation: Spindeldreier, Claudia Katharina (2018) Dosimetry with ionization chambers and optically stimulated luminescence detectors in magnetic fields. [Dissertation] document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/24050/1/20171109ThesisFinal_Spindeldreier.pdf