<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children"^^ . "Background: Respiratory syncytial virus (RSV) is the most important cause of severe acute respiratory tract infection in young children. Alere i RSV is a novel molecular rapid test which identifies respiratory syncytial virus in less than 13 min.\r\n\r\nMethods: We evaluated the clinical performance of the Alere i RSV assay in a pediatric point-of-care setting during winter season 2016 / 2017. Test results from 518 nasopharyngeal swab samples were compared to a real-time reverse transcription PCR reference standard.\r\n\r\nResults: The overall sensitivity and specificity of the Alere i RSV test assay was 93% (CI95 89% – 96%) and 96% (CI95 93% – 98%), respectively. Alere i RSV performed well in children of all age groups. An optimal sensitivity of 98% (CI95 94% - 100%) and specificity of 96% (CI95 90% - 99%) was obtained in children < 6 months. In children ≥ 2 years, sensitivity and specificity remained at 87% (CI95 73% – 96%) and 98% (CI95 92% – 100%), respectively. False negative Alere i RSV test results mostly occurred in samples with low viral load (mean CT value 31.1; CI95 29.6 – 32.6). The Alere i RSV assay is easy to use and can be operated after minimal initial training. Test results are available within 13 min, with most RSV positive samples being identified after approximately 5 min. \r\n\r\nConclusion: The Alere i RSV assay has the potential to facilitate the detection of RSV in pediatric point-of-care settings."^^ . "2017" . . . "17" . "767" . . "BioMed Central ; Springer"^^ . . . "BMC Infectious Diseases"^^ . . . "14712334" . . . . . . . . . . . . . . . . . "Clara M."^^ . "Ihling"^^ . "Clara M. Ihling"^^ . . "Julia"^^ . "Tabatabai"^^ . "Julia Tabatabai"^^ . . "Johannes"^^ . "Pfeil"^^ . "Johannes Pfeil"^^ . . "Paul"^^ . "Schnitzler"^^ . "Paul Schnitzler"^^ . . "Sarah V."^^ . "Schnee"^^ . "Sarah V. Schnee"^^ . . . . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children (PDF)"^^ . . . "12879_2017_Article_2855.pdf"^^ . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #24267 \n\nPerformance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children\n\n" . "text/html" . . . "610 Medizin"@de . "610 Medical sciences Medicine"@en . .