eprintid: 24344 rev_number: 14 eprint_status: archive userid: 1589 dir: disk0/00/02/43/44 datestamp: 2018-05-30 09:09:34 lastmod: 2024-03-09 20:38:18 status_changed: 2018-05-30 09:09:34 type: article metadata_visibility: show creators_name: Ojeda, I. Cherrez creators_name: Vanegas, E. creators_name: Felix, M. creators_name: Mata, V. creators_name: Cherrez, S. creators_name: Simancas-Racines, D. creators_name: Greiding, L. creators_name: Cano, J. creators_name: Cherrez, A. creators_name: Carlos Calderon, Juan C title: Etiology of chronic urticaria: the Ecuadorian experience subjects: ddc-610 divisions: i-61000 abstract: Background: The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there is an association between the etiology and its treatment. Methods: We performed a retrospective study involving 112 patients diagnosed with CU using a Checklist for a complete chronic urticaria medical history. Demographic and clinical variables were collected. The etiology of CU was classified using the EAACI/GA2LEN/EDF/WAO guideline. Descriptive analyses were performed for demographical and clinical variables. Chi square tests were applied to analyze the fit of distribution and the independence of variables. P values less than 0.05 were considered significant. Results: Among all the patients, 76.8% were diagnosed with chronic spontaneous urticaria (CSU), of which 22.3% had a known etiology or possible exacerbating condition. Food allergy was identified as the most common accompanying condition in patients with CSU (10.7%) (p < 0.01).. On the other hand, 23.2% inducible urticarias (CIndU) were indentified; dermographism was the most common (10.7%) (p < 0.01). Regarding treatment regimens, sg-H1-antihistamines alone represented the highest proportion (44.6%). The combination of any H1-antihistamine plus other drug was a close second (42.0%) (p < 0.01). Almost 48% of CSUs of unknown etiology were treated with any antihistamine plus another drug. In patients with known etiology, sg-antihistamines alone (44.0%) was the most common management. In addition, 53.8% of CIndUs were treated with sg-antihistamines alone. Though, these associations were not statistically significant. Conclusion: CSU is the most frequent subtype of CU. Modern non-sedating antihistamines in licensed doses are the drug of choice. Nevertheless, a great proportion of patients require the addition of another type of medication. date: 2018 publisher: Wolters Kluwer Health Lippincott Williams & Wilkins id_scheme: DOI ppn_swb: 1653356073 own_urn: urn:nbn:de:bsz:16-heidok-243444 language: eng bibsort: OJEDAICHERETIOLOGYOF2018 full_text_status: public publication: World Allergy Organization Journal volume: 11 number: 1 place_of_pub: Hagerstown, Md. pagerange: 1-8 issn: 1939-4551 citation: Ojeda, I. Cherrez ; Vanegas, E. ; Felix, M. ; Mata, V. ; Cherrez, S. ; Simancas-Racines, D. ; Greiding, L. ; Cano, J. ; Cherrez, A. ; Carlos Calderon, Juan C (2018) Etiology of chronic urticaria: the Ecuadorian experience. World Allergy Organization Journal, 11 (1). pp. 1-8. ISSN 1939-4551 document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/24344/1/40413_2017_Article_181.pdf