title: GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics creator: Tintle, Nathan L. creator: Fardo, David W. creator: de Andrade, Mariza creator: Aslibekyan, Stella creator: Bailey, Julia N. creator: Bermejo, Justo Lorenzo creator: Cantor, Rita M. creator: Ghosh, Saurabh creator: Melton, Philip creator: Wang, Xuexia creator: MacCluer, Jean W. creator: Almasy, Laura subject: 610 subject: 610 Medical sciences Medicine description: GAW20 provided a platform for developing and evaluating statistical methods to analyze human lipid-related phenotypes, DNA methylation, and single-nucleotide markers in a study involving a pharmaceutical intervention. In this article, we present an overview of the data sets and the contributions analyzing these data. The data, donated by the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) investigators, included data from 188 families (Nā€‰=ā€‰1105) which included genome-wide DNA methylation data before and after a 3-week treatment with fenofibrate, single-nucleotide polymorphisms, metabolic syndrome components before and after treatment, and a variety of covariates. The contributions from individual research groups were extensively discussed prior, during, and after the Workshop in groups based on discussion themes, before being submitted for publication. publisher: BioMed Central date: 2018 type: Article type: info:eu-repo/semantics/article type: NonPeerReviewed format: application/pdf identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/25469/1/12919_2018_Article_113.pdf identifier: DOI:https://doi.org/10.1186/s12919-018-0113-1 identifier: urn:nbn:de:bsz:16-heidok-254699 identifier: Tintle, Nathan L. ; Fardo, David W. ; de Andrade, Mariza ; Aslibekyan, Stella ; Bailey, Julia N. ; Bermejo, Justo Lorenzo ; Cantor, Rita M. ; Ghosh, Saurabh ; Melton, Philip ; Wang, Xuexia ; MacCluer, Jean W. ; Almasy, Laura (2018) GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics. BMC Proceedings, 12 (9:26). pp. 1-3. ISSN 1753-6561 relation: https://archiv.ub.uni-heidelberg.de/volltextserver/25469/ rights: info:eu-repo/semantics/openAccess rights: Please see front page of the work (Sorry, Dublin Core plugin does not recognise license id) language: eng