eprintid: 25469
rev_number: 10
eprint_status: archive
userid: 1589
dir: disk0/00/02/54/69
datestamp: 2018-10-23 10:51:24
lastmod: 2018-11-29 12:27:32
status_changed: 2018-10-23 10:51:24
type: article
metadata_visibility: show
creators_name: Tintle, Nathan L.
creators_name: Fardo, David W.
creators_name: de Andrade, Mariza
creators_name: Aslibekyan, Stella
creators_name: Bailey, Julia N.
creators_name: Bermejo, Justo Lorenzo
creators_name: Cantor, Rita M.
creators_name: Ghosh, Saurabh
creators_name: Melton, Philip
creators_name: Wang, Xuexia
creators_name: MacCluer, Jean W.
creators_name: Almasy, Laura
title: GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics
subjects: 610
divisions: 911800
abstract: GAW20 provided a platform for developing and evaluating statistical methods to analyze human lipid-related phenotypes, DNA methylation, and single-nucleotide markers in a study involving a pharmaceutical intervention. In this article, we present an overview of the data sets and the contributions analyzing these data. The data, donated by the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) investigators, included data from 188 families (N = 1105) which included genome-wide DNA methylation data before and after a 3-week treatment with fenofibrate, single-nucleotide polymorphisms, metabolic syndrome components before and after treatment, and a variety of covariates. The contributions from individual research groups were extensively discussed prior, during, and after the Workshop in groups based on discussion themes, before being submitted for publication.
date: 2018
publisher: BioMed Central
id_scheme: DOI
id_number: https://doi.org/10.1186/s12919-018-0113-1
ppn_swb: 1657382206
own_urn: urn:nbn:de:bsz:16-heidok-254699
language: eng
bibsort: TINTLENATHGAW20METHO2018
full_text_status: public
publication: BMC Proceedings
volume: 12
number: 9:26
place_of_pub: London
pagerange: 1-3
issn: 1753-6561
citation:   Tintle, Nathan L. ; Fardo, David W. ; de Andrade, Mariza ; Aslibekyan, Stella ; Bailey, Julia N. ; Bermejo, Justo Lorenzo ; Cantor, Rita M. ; Ghosh, Saurabh ; Melton, Philip ; Wang, Xuexia ; MacCluer, Jean W. ; Almasy, Laura  (2018) GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics.  BMC Proceedings, 12 (9:26).  pp. 1-3.  ISSN 1753-6561     
document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/25469/1/12919_2018_Article_113.pdf