<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals"^^ . "In mammals, X-chromosome inactivation (XCI) re-establishes the dosage balance between male and female gene expression levels. However, up to a third of the X-linked genes escape this phenomenon with varying degrees of consistency across tissues, cell lines, or individuals. Here, I take advantage of a new extensive developmental dataset for several organs and species to explore the developmental dimension of sex chromosomes expression levels. I find that only a small fraction of genes escaping XCI show a consistent female overexpression across development, organs, and species. The consistently sex-biased genes are almost exclusively either directly involved in the establishment of XCI, or are protein-coding genes with a broadly expressed Y homolog. The conservation of the sex-bias of these genes across species suggests that they might be responsible for the evolution of escape from XCI. I also present and test a model of allelic contribution to the total expression levels of X-linked genes using marsupial bulk tissue RNA sequencing data. Finally, I describe my contribution to a study of sex-biased micro-RNAs in mammals."^^ . "2018" . . . . . . . "Tania"^^ . "Studer"^^ . "Tania Studer"^^ . . . . . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals (PDF)"^^ . . . "Thesis_Tania_2ref.pdf"^^ . . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals (Other)"^^ . . . . . . "preview.jpg"^^ . . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals (Other)"^^ . . . . . . "medium.jpg"^^ . . . "The developmental sex-biased expression of genes escaping X chromosome inactivation across mammals (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #25740 \n\nThe developmental sex-biased expression of genes escaping X chromosome inactivation across mammals\n\n" . "text/html" . . . "000 Allgemeines, Wissenschaft, Informatik"@de . "000 Generalities, Science"@en . . . "500 Naturwissenschaften und Mathematik"@de . "500 Natural sciences and mathematics"@en . . . "570 Biowissenschaften, Biologie"@de . "570 Life sciences"@en . . . "590 Tiere (Zoologie)"@de . "590 Zoological sciences"@en . .