<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "On the Simultaneous Quantification of Flow Velocities and Relaxation Constants Through Magnetic Resonance Fingerprinting"^^ . "In this thesis, the development of a novel magnetic resonance imaging (MRI) pulse sequence\r\nbased on magnetic resonance fingerprinting (MRF) is presented. The proposed technique,\r\ntermed “Flow-MRF”, allows time-resolved velocities and relaxation constants to be quantified\r\nsimultaneously, in shorter acquisition times than conventional MR-based velocimetry.\r\nThe simultaneous quantification of both sets of parameters was achieved by formulating the\r\ncombined problem in the MRF framework. An MRF pattern was designed to create minimal\r\ncoupling between the relaxometric and velocimetric parameter encoding.\r\nFlow-MRF was validated and tested in simulations, phantom experiments, and an in vivo\r\nstudy targeting the popliteal artery and the gastrocnemius muscle. In each investigation,\r\nFlow-MRF quantified relaxation constants and flow velocities in strong agreement with literature\r\nand reference measurements. Furthermore, the use of high velocity encoding moments\r\n(Δm1 = 60 mT/m·ms^2) was demonstrated while maintaining a range of correctly quantifiable\r\nvelocities beyond 800 cm/s. In the volunteer study, Flow-MRF determined an average\r\nlongitudinal relaxation time of (1384±75) ms and a transverse relaxation time of (26±4) ms\r\nin the gastrocnemius muscle. The average velocity deviation over all three volunteers between\r\nFlow-MRF and the reference was (-2.6±5.2) cm/s. Lastly, the potential to quantify the complete\r\nReynolds stress tensor with Flow-MRF was investigated and shown in a stenotic flow\r\nphantom experiment.\r\nFlow‐MRF presents a novel method of quantifying velocities in up to fourfold shorter measurement\r\ntimes than conventional velocity mapping techniques, while simultaneously providing\r\nrelaxometric maps of static tissue. These improvements can potentially be helpful in the\r\nassessment of pathologies such as arteriosclerosis."^^ . "2019" . . . . . . . "Sebastian"^^ . "Flassbeck"^^ . "Sebastian Flassbeck"^^ . . . . . . "On the Simultaneous Quantification of Flow Velocities and Relaxation Constants Through Magnetic Resonance Fingerprinting (PDF)"^^ . . . "dkfz - Diss -- Flassbeck, S - 2019 - On the Simultaneous Quantification of Flow Velocities and Relaxation Constants Through Magnetic Resonance Fingerprinting.pdf"^^ . . . "On the Simultaneous Quantification of Flow Velocities and Relaxation Constants Through Magnetic Resonance Fingerprinting (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #26414 \n\nOn the Simultaneous Quantification of Flow Velocities and Relaxation Constants Through Magnetic Resonance Fingerprinting\n\n" . "text/html" . . . "500 Naturwissenschaften und Mathematik"@de . "500 Natural sciences and mathematics"@en . . . "530 Physik"@de . "530 Physics"@en . . . "600 Technik, Medizin, angewandte Wissenschaften"@de . "600 Technology (Applied sciences)"@en . .