eprintid: 26419 rev_number: 14 eprint_status: archive userid: 1589 dir: disk0/00/02/64/19 datestamp: 2019-08-01 14:32:58 lastmod: 2019-08-22 09:39:02 status_changed: 2019-08-01 14:32:58 type: article metadata_visibility: show creators_name: Wensing, Michel creators_name: Grol, Richard title: Knowledge translation in health: how implementation science could contribute more subjects: ddc-610 divisions: i-620100 keywords: Knowledge transfer, Implementation science, Quality improvement, Research policy abstract: Background: Despite increasing interest in research on how to translate knowledge into practice and improve healthcare, the accumulation of scientific knowledge in this field is slow. Few substantial new insights have become available in the last decade. Main body: Various problems hinder development in this field. There is a frequent misfit between problems and approaches to implementation, resulting in the use of implementation strategies that do not match with the targeted problems. The proliferation of concepts, theories and frameworks for knowledge transfer – many of which are untested – has not advanced the field. Stakeholder involvement is regarded as crucial for successful knowledge implementation, but many approaches are poorly specified and unvalidated. Despite the apparent decreased appreciation of rigorous designs for effect evaluation, such as randomized trials, these should remain within the portfolio of implementation research. Outcome measures for knowledge implementation tend to be crude, but it is important to integrate patient preferences and the increased precision of knowledge. Conclusions: We suggest that the research enterprise be redesigned in several ways to address these problems and enhance scientific progress in the interests of patients and populations. It is crucially important to establish substantial programmes of research on implementation and improvement in healthcare, and better recognize the societal and practical benefits of research. date: 2019 publisher: BioMed Central id_scheme: DOI ppn_swb: 1671849051 own_urn: urn:nbn:de:bsz:16-heidok-264199 language: eng bibsort: WENSINGMICKNOWLEDGET2019 full_text_status: public publication: BMC Medicine volume: 17 number: 88 place_of_pub: London pagerange: 1-6 issn: 1741-7015 citation: Wensing, Michel ; Grol, Richard (2019) Knowledge translation in health: how implementation science could contribute more. BMC Medicine, 17 (88). pp. 1-6. ISSN 1741-7015 document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/26419/1/12916_2019_Article_1322.pdf