<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Scalable Instance Segmentation for Microscopy"^^ . "Modern microscopy techniques acquire images at very high rates, high spatial resolution and with a large field of view.\r\nTo analyze the large image data-sets acquired with such microscopes, accurate and scalable automated analysis is desperately needed.\r\nA key component is the instance segmentation of structures of interest, such as cells, neurons or organelles.\r\n\r\nIn this thesis, we develop scalable methods for boundary based instance segmentation. We make use of Lifted Multicut graph partitioning and develop a method achieving state-of-the-art results on challenging benchmark data-sets.\r\nIn order to scale this approach up, we introduce a new approximate solver for Multicut and Lifted Multicut, which can solve problems that were previously infeasible.\r\nWe further establish a method to incorporate domain knowledge into the segmentation problem, which can significantly improve quality.\r\nTo overcome the brittleness of seeded watersheds, used extensively in segmentation for microscopy, we introduce the Mutex Watershed. This efficient algorithm can segment images directly from pixels without the need for seeds or thresholds.\r\nFinally, we apply our methods in collaborative work, demonstrating their utility to answer biological research questions.\r\n\r\nIn summary, our contributions enable scalable instance segmentation, thus eliminating one of the major obstacles to the automated analysis of large microscopy data-sets."^^ . "2021" . . . . . . . "Constantin"^^ . "Pape"^^ . "Constantin Pape"^^ . . . . . . "Scalable Instance Segmentation for Microscopy (PDF)"^^ . . . "phd-thesis-cpape.pdf"^^ . . . "Scalable Instance Segmentation for Microscopy (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Scalable Instance Segmentation for Microscopy (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Scalable Instance Segmentation for Microscopy (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Scalable Instance Segmentation for Microscopy (Other)"^^ . . . . . . "small.jpg"^^ . . . "Scalable Instance Segmentation for Microscopy (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #30147 \n\nScalable Instance Segmentation for Microscopy\n\n" . "text/html" . . . "004 Informatik"@de . "004 Data processing Computer science"@en . . . "530 Physik"@de . "530 Physics"@en . . . "570 Biowissenschaften, Biologie"@de . "570 Life sciences"@en . .