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primary topic: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking

Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking
type: Article
abstract: Carbon-ion beam radiotherapy has been developed as a highly effective modality for cancer treatment. Based on the precise dose distributions of carbon-ion treatments, a better sparing of healthy organs surrounding the tumor site compared to the standard photon radiotherapy are provided. However, dose distributions in car-bon-ion beam radiotherapy are more prone to uncertainties. Therefore, strategies to monitor the ion beam during a treatment delivery, ideally directly in the patient, are of great importance. In this thesis, a non-invasive methodology to measure the lateral pencil beam positions in the patient has been developed. It is based on detection and tracking of charged nuclear fragments leaving the treated patient as secondary radiation. The performance of the developed methodology was investigated in patient-like models mimicking clinical situations at the HIT facility in Heidelberg, Germany. Moreover, the developed methodology has been tested for the first time during a real patient treatment. Precision, accuracy and effectivity of the developed method were found to be clinically attractive compared to the maximal accepted uncertainties of 1 mm. Additionally, the beam movement was aiming towards online carbon-ion beam monitoring. This independent beam monitoring methodology is ready to be evaluated on a larger patient group in a clinical study.
date: 2021
author list: authors
type: EPrint
type: DoctoralThesisEPrint
is part of: repository
has document: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
has document: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (Other)
subject: 500 Naturwissenschaften und Mathematik
subject: 530 Physik
subject: 610 Medizin

Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
type: Document
has file: PhD_Thesis_RFelixBautista.pdf
has part: PhD_Thesis_RFelixBautista.pdf

Renato Félix Bautista
type: Person
given name: Renato
family name: Félix Bautista

Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (Other)
type: Document
is version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
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Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (Other)
type: Document
is version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
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Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (Other)
type: Document
is version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
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Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (Other)
type: Document
is version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
is volatile version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
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Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (Other)
type: Document
is version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
is volatile version of: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking (PDF)
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HTML Summary of #30155 Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking
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primary topic: Monitoring of lateral positions of therapeuthic carbon-ion pencil beams using secondary ion tracking

500 Naturwissenschaften und Mathematik
type: Concept
preferred label: 500 Natural sciences and mathematics @en

530 Physik
type: Concept
preferred label: 530 Physics @en

610 Medizin
type: Concept
preferred label: 610 Medical sciences Medicine @en