title: Perplexity – a new predictor of cognitive changes in spoken language? – results of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE)
creator: Frankenberg, Claudia
creator: Weiner, Jochen
creator: Schultz, Tanja
creator: Knebel, Maren
creator: Degen, Christina
creator: Wahl, Hans-W.
creator: Schroeder, Johannes
subject: ddc-150
subject: 150 Psychology
description: Abstract: In addition to memory loss, progressive deterioration of speech and language skills is among the main symptoms at the onset of Alzheimer’s disease (AD) as well as in mild cognitive impairment (MCI). Detailed interview analyses demonstrated early symptoms years before the onset of AD/MCI. Automatic speech processing could be a promising approach to identifying underlying mechanisms in larger studies or even support diagnostics. Perplexity as a measure of predictability of text could be a sensitive indicator of cognitive deterioration. Therefore, voice recordings from the Interdisciplinary Longitudinal Study on Adult Development and Aging were analyzed with regard to neuropsychological parameters in participants that develop MCI/AD or remain cognitively healthy. Preliminary results indicate that perplexity predicts severity of cognitive deficits and information processing speed obtained 10–12 years later in participants who developed MCI/AD in contrast to those who stayed healthy. Findings support the heuristic value of research on the diagnostic potential of automatic speech processing.
publisher: De Gruyter Mouton
date: 2019
type: Article
type: info:eu-repo/semantics/article
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/32749/1/10.1515_lingvan-2018-0026.pdf
identifier: DOI:10.11588/heidok.00032749
identifier: https://doi.org/10.1515/lingvan-2018-0026
identifier: urn:nbn:de:bsz:16-heidok-327497
identifier:   Frankenberg, Claudia ; Weiner, Jochen ; Schultz, Tanja ; Knebel, Maren ; Degen, Christina ; Wahl, Hans-W. ; Schroeder, Johannes  (2019) Perplexity – a new predictor of cognitive changes in spoken language? – results of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE).  Linguistics Vanguard, 5 (s2).  pp. 1-10.  ISSN 2199-174X     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/32749/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng