eprintid: 32749
rev_number: 17
eprint_status: archive
userid: 5878
dir: disk0/00/03/27/49
datestamp: 2023-01-20 15:01:19
lastmod: 2023-02-02 12:55:27
status_changed: 2023-01-20 15:01:19
type: article
metadata_visibility: show
creators_name: Frankenberg, Claudia
creators_name: Weiner, Jochen
creators_name: Schultz, Tanja
creators_name: Knebel, Maren
creators_name: Degen, Christina
creators_name: Wahl, Hans-W.
creators_name: Schroeder, Johannes
title: Perplexity – a new predictor of cognitive changes in spoken language? – results of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE)
subjects: ddc-150
divisions: i-100200
divisions: i-100600
divisions: i-999999
keywords: language and aging, speech processing, Alzheimer’s disease, mild cognitive impairment
note: Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz bzw. Nationallizenz frei zugänglich. *** This publication is freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
abstract: Abstract: In addition to memory loss, progressive deterioration of speech and language skills is among the main symptoms at the onset of Alzheimer’s disease (AD) as well as in mild cognitive impairment (MCI). Detailed interview analyses demonstrated early symptoms years before the onset of AD/MCI. Automatic speech processing could be a promising approach to identifying underlying mechanisms in larger studies or even support diagnostics. Perplexity as a measure of predictability of text could be a sensitive indicator of cognitive deterioration. Therefore, voice recordings from the Interdisciplinary Longitudinal Study on Adult Development and Aging were analyzed with regard to neuropsychological parameters in participants that develop MCI/AD or remain cognitively healthy. Preliminary results indicate that perplexity predicts severity of cognitive deficits and information processing speed obtained 10–12 years later in participants who developed MCI/AD in contrast to those who stayed healthy. Findings support the heuristic value of research on the diagnostic potential of automatic speech processing.
date: 2019
publisher: De Gruyter Mouton
id_scheme: DOI
id_number: 10.11588/heidok.00032749
official_url: https://doi.org/10.1515/lingvan-2018-0026
ppn_swb: 183294784X
own_urn: urn:nbn:de:bsz:16-heidok-327497
language: eng
bibsort: FRANKENBERPERPLEXITY2019
full_text_status: public
publication: Linguistics Vanguard
volume: 5
number: s2
place_of_pub: Berlin ; New York, NY
pagerange: 1-10
issn: 2199-174X
edition: Zweitveröffentlichung
citation:   Frankenberg, Claudia ; Weiner, Jochen ; Schultz, Tanja ; Knebel, Maren ; Degen, Christina ; Wahl, Hans-W. ; Schroeder, Johannes  (2019) Perplexity – a new predictor of cognitive changes in spoken language? – results of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE).  Linguistics Vanguard, 5 (s2).  pp. 1-10.  ISSN 2199-174X     
document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/32749/1/10.1515_lingvan-2018-0026.pdf