TY  - GEN
UR  - https://archiv.ub.uni-heidelberg.de/volltextserver/34452/
Y1  - 2024///
A1  - Dietrich, Kilian Alexander
CY  - Heidelberg
AV  - public
ID  - heidok34452
TI  - Development of radiofrequency coils for magnetic resonance-guided particle therapy
N2  - The aim of this work was to develop radiofrequency coils suitable for magnetic resonance (MR)-guided particle therapy. For two different MR systems (1.5 T, 0.25 T), a transmit/receive body coil and a receive-only calf coil were designed, constructed, optimized and built. The two coils are characterized by a very thin conductor (thickness:
35 ?m) and high radiation transparency to enable precise particle therapy with simultaneous MR imaging. A negligible water equivalent thickness (WET) of the conductor (WET: 0.18?0.19 mm) was measured based on the dose distribution in a water column. In addition, both MR coils can be rotated, allowing flexible particle therapy with multi-angle irradiation. A high homogeneity of the transmit (body coil)
and receive (both coils) fields was confirmed in homogeneous phantoms for different rotation angles of the MR coils. The body coil also achieved sufficient transmit power efficiency (0.18?0.27 ?T/?W) in the central slice for a complete rotation of the phantom. In terms of image quality, the signal-to-noise ratio (SNR) was measured in a homogeneous
phantom, where the body coil (SNR: 109?156) and the calf coil (SNR: 74?90) outperformed commercial coils. Furthermore, the functionality of the two coils was
demonstrated in an anthropomorphic phantom (body coil) and in vivo (calf coil).
ER  -