TY - GEN N2 - Improvements for Medical Imaging Robotic computer tomography systems offer a wide range possibilities for non-circular and patient specific trajectories. These could reduce metal artifacts, improve the image quality or increase the available space for the practitioners. But every trajectory needs to be calibrated to reconstruct the CT image. There are two main approaches, an offline calibration uses a special phantom that has to be imaged before the patient and the online calibration where the trajectory is calibrated with the images acquired from using a prior CT image. In chapter 5, a method for calibrating arbitrary Cone-Beam Computed Tomography (CBCT) trajectories (FORCASTER) is developed. It detects and matches feature points in simulated projections and acquired projections. These paired feature points are then used to correct the projection parameters by directly calculating the correction factor or with a minimization algorithm, which is also presented in this part. To simulate projections a prior image of the object is needed, but it is also shown that this calibration functions if the prior image has some differences compared to the object that is currently imaged. The FORCASTER algorithm achieves similar calibration results when compared to state-of-the-art algorithms. The following chapter 6 introduces FORCAST-EST, an extension for the FORCASTER algorithm, which estimates the starting parameters for the calibration. This allows the calibration of trajectories that come without positional and rotational data for the individual projections. It simulates projections in a grid and then compares every acquired projection to the grid, first in a coarse search and then in the surrounding of the best matches. The estimates are sufficient to calibrate the trajectory with a similar accuracy as FORCASTER using the regular starting parameters recorded by the CBCT system. In chapter 3 of this thesis, an algorithm for detecting arteries in dynamic contrast enhanced MRI images is presented. Through thresholding, flood fill and morphological operations, a mask for the artery at the time point where the initial wave of contrast agent arrives is created. The process is deterministic and independent of the user experience. Since the annotation of the artery has a strong impact on the calculated perfusion values, helps this algorithm with reproducibility and comparability of perfusion imaging. The chapter 4 presents a web-based MRI image generator for teaching students. It allows the students to choose different sequences and set the relevant parameters, and they can then see how it changes the resulting MRI image. The software runs completely inside the browser and is open source1 . The presented work show algorithms that help in the imaging process by improving reproducability and comparability or in reconstructing CBCT volumes. ID - heidok34473 KW - Kalibrierung CY - Heidelberg UR - https://archiv.ub.uni-heidelberg.de/volltextserver/34473/ AV - public A1 - Tönnes, Christian Y1 - 2024/// TI - Automatic interventional Imaging for the Parametrisation of Vascular Structures ER -