title: OligoChannel Spectral Analysis in stereotactic laser neurosurgery
creator: Greger, Klaus
subject: ddc-530
subject: 530 Physics
description: In stereotactic laser neurosurgery a tumor in the human brain is resected by a pulsed high energy laser beam. The laser beams for diagnosis and ablation of cancerous tissue are supplied through a probe. The whole resection is planned with a computer system. These planning data are based on previously obtained CT and MRT imaging. During the operation the complete process (diagnosis and resection) is guided and controlled by a computer system. One important part of the surgical system is the OligoChannel Spectrum Analyzer (OCSA), of which the principles and development are described in this work. The OCSA analyzes the autofluorescence spectrum of each observed tissue point in order to determine its kind. This is possible since autofluorescence spectra of healthy and cancerous tissue show characteristic differences. In contrast to commonly used techniques, the OCSA uses only a few detectors. By evaluation of the data obtained with the OCSA, an immediate decision can be made whether a specific tissue point should  be ablated or not. To demonstrate the new technique, some results obtained with different tissue samples (human kidney and various mouse tissues) will be presented.
date: 2003
type: Dissertation
type: info:eu-repo/semantics/doctoralThesis
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/3497/1/PromotionFinal.pdf
identifier: DOI:10.11588/heidok.00003497
identifier: urn:nbn:de:bsz:16-opus-34973
identifier:   Greger, Klaus  (2003) OligoChannel Spectral Analysis in stereotactic laser neurosurgery.  [Dissertation]     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/3497/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng