eprintid: 36578
rev_number: 13
eprint_status: archive
userid: 5878
dir: disk0/00/03/65/78
datestamp: 2025-05-16 11:52:43
lastmod: 2025-05-27 12:33:49
status_changed: 2025-05-16 11:52:43
type: article
metadata_visibility: show
creators_name: Riedel, Fabian
creators_name: Hahn, Markus
creators_name: Bader, Werner
creators_name: Schäfgen, Benedikt
creators_name: Fastner, Sarah
creators_name: Hennigs, André
creators_name: Gomez, Christina
creators_name: Stieber, Anne
creators_name: Fastner, Christian
creators_name: Wallwiener, Markus
creators_name: Golatta, Michael
creators_name: Heil, Jörg
creators_name: Fallenberg, Eva Maria
title: Management of Patients with Breast Biopsy under Anti-Coagulation or Anti-Platelet Therapy: Results of a Survey of German Experts
ispublished: pub
subjects: ddc-610
divisions: i-61000
divisions: i-65000
divisions: i-910400
keywords: Breast, Biopsy, Anti-coagulation, Anti-platelet therapy, Expert survey
note: Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz bzw. Nationallizenz frei zugänglich. *** This publication is freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
abstract: Introduction: Pre-therapeutic histologic diagnosis through image-guided core needle biopsy (CNB) or vacuum-assisted biopsy (VAB) for suspicious breast findings is a standard procedure. Despite the moderate risk of bleeding, a significant proportion of patients are on temporary or permanent anti-coagulation therapy (ACT) or anti-platelet therapy (APT). Currently, there are no established guidelines for managing biopsies in such patients, leading to varying approaches in clinical practice. Methods: An online survey was conducted among all members of the breast ultrasound working group at the German Society for Ultrasound in Medicine (DEGUM) and the working group for breast diagnostics at the German Radiology Society (DRG). It included <i>n</i> = 51 questions about individual risk perception of biopsy-related bleeding complications and the specific management of biopsies on ACT/APT. Results: A total of 332 experts participated, with 51.8% reporting the absence of a standardized management plan for breast biopsies on ACT/APT. Concerning specific ACT/APT medications, the survey revealed discrepancies in risk perception and management: The majority preferred discontinuing medication with directly acting oral anti-coagulants (DOACs; CNB: 66.9%; VAB: 91.1%), phenprocoumon (CNB: 74.9%; VAB: 96.7%), or therapeutic heparin (CNB: 46.1%; VAB: 72.7%). However, there was a lower inclination to discontinue acetylsalicylic acid (ASA; CNB: 15.2%; VAB: 50.3%) or prophylactic heparin (CNB: 11.9%, VAB: 36.3%). Conclusion: Breast biopsies for patients on ASA or prophylactic heparin are deemed safe and part of standard clinical practice. However, despite available feasibility studies, conducting breast biopsies on ACT medications such as DOACs or phenprocoumon appears feasible only for a minority of experts.
date: 2024
date_type: published
publisher: Karger
id_scheme: DOI
id_number: 10.11588/heidok.00036578
official_url: https://doi.org/10.1159/000536079
ppn_swb: 1926870395
own_urn: urn:nbn:de:bsz:16-heidok-365783
language: eng
bibsort: RIEDELFABIMANAGEMENT2024
full_text_status: public
publication: Breast Care
volume: 19
number: 2
place_of_pub: Basel ; Freiburg, Br. ; Paris ; London ; New York, NY ; Bangalore ; Bangkok ; Shanghai ; Singapore ; Tokyo ; Sydney
pagerange: 87-95
pages: 9
issn: 1661-3791 (Druck-Ausg.); 1661-3805 (Online-Ausg.)
edition: Zweitveröffentlichung
citation:   Riedel, Fabian ; Hahn, Markus ; Bader, Werner ; Schäfgen, Benedikt ; Fastner, Sarah ; Hennigs, André ; Gomez, Christina ; Stieber, Anne ; Fastner, Christian ; Wallwiener, Markus ; Golatta, Michael ; Heil, Jörg ; Fallenberg, Eva Maria  (2024) Management of Patients with Breast Biopsy under Anti-Coagulation or Anti-Platelet Therapy: Results of a Survey of German Experts.  Breast Care, 19 (2).  pp. 87-95.  ISSN 1661-3791 (Druck-Ausg.); 1661-3805 (Online-Ausg.)     
document_url: https://archiv.ub.uni-heidelberg.de/volltextserver/36578/1/BRC536079.pdf