TY  - JOUR
EP  - 520
IS  - 5
SP  - 512
CY  - London
A1  - Mokry, Theresa
A1  - Pantke, Judith
A1  - Kauczor, Hans-Ulrich
A1  - Laun, Frederik B
A1  - Schlemmer, Heinz-Peter
A1  - Kuder, Tristan A
A1  - Bickelhaupt, Sebastian
N2  - Background 
Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries.
   Purpose 
To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries.
   Material and Methods 
 This prospective, single-centre study consisted of repeated 1.5-T and 3-T examinations in 30 female volunteers (mean age=27.9 years, age range=20.3?45.2 years) from July 2017 to September 2019. Multi b-value DWI 0, 50, 100, 800, 1500, 2000 s/mm 2 was acquired over three timepoints during the menstrual cycle. Ovaries were segmented at b = 1500 s/mm 2 . Median apparent diffusion coefficient (ADC) and advanced kurtosis parameters D app and K app were calculated. Statistical analysis was performed with the variations of diffusivity variables being compared between 1.5-T and 3-T MRI using a Mann?Whitney rank-sum test. 
   Results 
 Median ADC and D app (µm²/ms) did not statistically differ. Median ADC were 1.509 (range=1.371?1.610), 1.619 (range=1.463?1.747), and 1.511 (range=1.423?1.639) at 1.5 T; 1.542 (range=1.428?1.682), 1.658 (range=1.510?1.806), and 1.572 (range=1.455?1.709) at 3 T ( P = 0.14, 0.19, and 0.07), whereas median D app were 2.024 (range=1.913?2.152), 2.192 (range=2.010?2.327), and 2.045 (range=1.958?2.170) at 1.5 T; 2.013 (range=1.952?2.188), 2.179 (range=2.018?2.327), and 2.082 (range=1.959?2.194) at 3 T ( P = 0.77, 0.99, and 0.34) for timepoints 1, 2, and 3, respectively. Statistical comparison of K app revealed significant differences for all timepoints: 0.629 (range=0.595?0.652), 0.604 (range=0.574?0.651), and 0.622 (range=0.581?0.664) at 1.5 T; 0.601 (range=0.563?0.626), 0.567 (range=0.526?0.633), and 0.599 (range=0.541?0.650) at 3 T ( P < 0.001, 0.005, and 0.03). 
   Conclusion 
Diffusivity mapping in the ovaries provides similar absolute median diffusion values, but statistically significant differences in absolute kurtosis values between 1.5 T and 3 T.
PB  - Sage
TI  - Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI
ID  - heidok37519
VL  - 66
JF  - Acta Radiologica
N1  - Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz bzw. Nationallizenz frei zugänglich. *** This publication is freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
UR  - https://doi.org/10.1177/02841851241313021
AV  - restricted
Y1  - 2025///
SN  - 0284-1851
KW  - Genital
KW  -  reproductive
KW  -  magnetic resonance diffusion/perfusion
KW  -  ovaries
KW  -  adults
ER  -