title: The Role of Solvent in the Protein Dynamical Transition
creator: Tournier, Alexander Louis
subject: ddc-570
subject: 570 Life sciences
description: Experimental and computer simulation studies have revealed the presence of a transition in the dynamics of hydrated proteins around 220 K. This transition has been compared with that of a glass phase transition. It manifests itself by a nonlinear behavior in the temperature dependence of the average atomic mean-square displacements and involves an increase of the amplitude of protein dynamics. This increase in flexibility has been correlated with the onset of protein activity. In this thesis, the mechanisms behind the protein dynamical transition are explored using molecular dynamics simulations and neutron scattering experiments.
date: 2003
type: Dissertation
type: info:eu-repo/semantics/doctoralThesis
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/4377/1/thesis-NoPub.pdf
identifier: DOI:10.11588/heidok.00004377
identifier: urn:nbn:de:bsz:16-opus-43779
identifier:   Tournier, Alexander Louis  (2003) The Role of Solvent in the Protein Dynamical Transition.  [Dissertation]     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/4377/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng