TY  - GEN
UR  - https://archiv.ub.uni-heidelberg.de/volltextserver/5078/
KW  - Superposition 
KW  -  Pencil Beam 
KW  -  IMRT 
KW  -  3DCRT 
KW  -  Dosisberechnungdose calculation 
KW  -  optimization 
KW  -  IMRT 
KW  -  3DCRT 
KW  -  superposition 
KW  -  pencil beam
Y1  - 2004///
A1  - Scholz, Christian Johannes
AV  - public
ID  - heidok5078
TI  - Development and Evaluation of Advanced Dose Calculations for Modern Radiation Therapy Techniques
N2  - In modern radiotherapy, complex treatments are applied even inside inhomogeneous media like the lung or the head&neck region, where commonly used pencil beam algorithms often fail to predict precisely the physical radiation dose distribution. Thus the clinical outcome of the treatment can not be properly evaluated by physicians. By using more sophisticated dose calculations based on superposition or Monte Carlo techniques this problem would be reduced or would actually disappear, since they exactly account for intricate tissue inhomogeneities. However, up to now the enhanced calculation times have deferred their use in clinical daily routine planning at most therapy centers. In the presented work algorithms based on both superposition and Monte Carlo methods were implemented which precisely predict the dose even inside inhomogeneous tissues within acceptable calculation times. After thorough acceptance tests both algorithms were integrated into the clinical environment at the DKFZ both for the optimization of complex treatments applying fluence patterns with modulated intensities as well as for the calculation of their dose distributions. Their outcome in particular for inhomogeneous clinical lung and head&neck cases was evaluated through a study, which is also presented.
ER  -