title: Surface Enhanced Infrared Absorption on Au Nanoparticle Films for Optical Biosensing
creator: Enders, Dominik
subject: 530
subject: 530 Physics
description: This work is focussed on the investigation of surface enhanced infrared ab- sorption (SEIRA) of adsorbates on wet chemically prepared Au nanoparticle (AuNP) films. Optical properties of AuNP films were investigated with VIS spectroscopy; it was shown, that it is possible to describe these properties with effective media theories. The SEIRA activity was analysed by FTIR spectroscopy of adsorbates on AuNP films and comparison of the spectra with other FTIR spectra of the same adsorbate on a smooth SEIRA inactive Au film. A SEIRA factor of 26 was found for a film of discrete spherical AuNP, while in case of grown AuNP films a SEIRA enhancement of up to three or- ders of magnitude was achieved. The AuNP film morphology was characterized with scanning force microscopy and scanning electron microscopy. SEIRA ac- tive AuNP films were used as optical sensors for the ex-situ measurement of specific antibody-antigen coupling and the in-situ measurement of adsorbates (octadecanethiol, DNA) during the adsorption process.
date: 2005
type: Dissertation
type: info:eu-repo/semantics/doctoralThesis
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/6008/1/Dissertation_Enders.pdf
identifier: DOI:10.11588/heidok.00006008
identifier: urn:nbn:de:bsz:16-opus-60083
identifier:   Enders, Dominik  (2005) Surface Enhanced Infrared Absorption on Au Nanoparticle Films for Optical Biosensing.  [Dissertation]     
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/6008/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng