title: Development of a head-mount fiber scanning system for imaging in vivo creator: Sawinski, Jürgen subject: ddc-530 subject: 530 Physics description: In this thesis I will describe the basic concepts necessary for acquiring functional data from nerve tissue by application of two-photon laser scanning microscopy and its miniaturization for in vivo imaging in freely moving animals. The construction of a laser with enhanced repetition rate and the design of a novel non-resonant fiber scanning technique is emphasized. The increased repetition rate of the femtosecond laser source should decrease undesirable non-linear effects when transmitting ultra-short pulses with a single mode fiber. By implementing the prototype of a head-mounted microscope involving the novel fiber scanner and testing with fluorescent probes I can demonstrate its feasibility - not only for imaging in freely moving animals but for mobile laser scanning microscopy in general. date: 2005 type: Dissertation type: info:eu-repo/semantics/doctoralThesis type: NonPeerReviewed format: application/pdf identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/6025/1/thesis_sawinski_20051107.pdf identifier: DOI:10.11588/heidok.00006025 identifier: urn:nbn:de:bsz:16-opus-60256 identifier: Sawinski, Jürgen (2005) Development of a head-mount fiber scanning system for imaging in vivo. [Dissertation] relation: https://archiv.ub.uni-heidelberg.de/volltextserver/6025/ rights: info:eu-repo/semantics/openAccess rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html language: eng