title: Optimization of Scanning Parameters in Intensity Modulated Proton Therapy creator: Kang, Joanne H. subject: ddc-530 subject: 530 Physics description: As scanning systems for intensity modulated proton therapy (IMPT) gain prevalance in the market and make their way into cancer centers, there is a significant need for focused basic research. Understanding of the implications of active scanning and its many new parameters on radiation treatment must catch up to the rapidly developing technology, so that the flexibility and degrees of freedom offered by such scanners, and their benefits over passive scattering techniques, can be fully exploited to deliver the best treatment plans efficiently. Some key parameters such as the scan path, beam size, lateral scanning resolution, and depth scanning resolution, are assessed with the view to optimize them around the dosimetric plan quality and ease and speed of delivery. Optimization and selection algorithms are introduced to suggest how one may appropriately decide the parameters. The results of several patient plan comparison studies are offered to demonstrate the value of these tools and their likely feasibility in clinical practice. date: 2008 type: Dissertation type: info:eu-repo/semantics/doctoralThesis type: NonPeerReviewed format: application/pdf identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/8545/1/diss.pdf identifier: DOI:10.11588/heidok.00008545 identifier: urn:nbn:de:bsz:16-opus-85455 identifier: Kang, Joanne H. (2008) Optimization of Scanning Parameters in Intensity Modulated Proton Therapy. [Dissertation] relation: https://archiv.ub.uni-heidelberg.de/volltextserver/8545/ rights: info:eu-repo/semantics/openAccess rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html language: eng