<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion"^^ . "We have identified membrane components which are adjacent to type I and type II signal-anchor proteins during their insertion into the membrane of the ER. Using two different cross-linking approaches a 37-38-kD nonglycosylated protein, previously identified as P37 (High, S., D. G6dich, M. Wiedmann, T. A. Rapoport, and B. Dobberstein. 1991. J. Cell Biol. 113:35-44), was found adjacent to all the membrane inserted nascent chains used in this study. On the basis of immunoprecipitation, this ER protein was shown to be identical to the recently identified mammalian Sec61 protein. Thus, Sec61p is the principal cross-linking partner of both type I and type II signal-anchor proteins during their membrane insertion (this work), and of secretory proteins during their translocation (G-tdich, D., S. Prehn, E. Hartmann, K.-U. Kalies, and T. A. Rapoport. 1992. Cell. 71:489-503). We propose that membrane proteins of both orientations, and secretory proteins employ the same ER translocation sites, and that Sec61p is a core component of these sites."^^ . "1993" . . . "121" . "4" . . "The Journal of Cell Biology"^^ . . . . . . . . . . . . . . . . . . . . . . . . . "Stephen"^^ . "High"^^ . "Stephen High"^^ . . "Enno"^^ . "Hartmann"^^ . "Enno Hartmann"^^ . . "Bernhard"^^ . "Dobberstein"^^ . "Bernhard Dobberstein"^^ . . "Tom A."^^ . "Rapoport"^^ . "Tom A. Rapoport"^^ . . "Dirk"^^ . "Görlich"^^ . "Dirk Görlich"^^ . . "Soren S. L."^^ . "Andersen"^^ . "Soren S. L. Andersen"^^ . . "Siegfried"^^ . "Prehn"^^ . "Siegfried Prehn"^^ . . . . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion (PDF)"^^ . . . "High_1993_JCB.pdf"^^ . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion (Other)"^^ . . . . . . "indexcodes.txt"^^ . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Sec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #8568 \n\nSec61p is Adjacent to Nascent Type I and Type II Signal-Anchor Proteins during Their Membrane Insertion\n\n" . "text/html" . . . "570 Biowissenschaften, Biologie"@de . "570 Life sciences"@en . .