title: Identification of an H-2Kd gene using a specific cDNA probe
creator: Xin, J.-H.
creator: Kvist, S.
creator: Dobberstein, B.
subject: ddc-570
subject: 570 Life sciences
description: A cDNA clone known to code for a mouse histocompatibility (class I) antigen was found to contain a sequence specific for a subpopulation of H-2 genes. This unique sequence is located in the 3' non-coding region close to the stretch of poly(A) nucleotides. A subclone containing this fragment(pH-2d-5) has been used to select hybridizing mRNA. Translation of the mRNA in vitro shows that H-2Kd mRNA is selected. Southern blot analysis of DNA from congenic recombinant mice show that at least one gene containing this sequence is located at the K locus (region) of the major histocompatibility complex. This gene contains a 3.7-kb Bgml and a 13-kb EcoRI restriction endonuclease fragment. This gene has been isolated from a genomic DNA library. 
date: 1982
type: Article
type: info:eu-repo/semantics/article
type: NonPeerReviewed
format: application/pdf
identifier: https://archiv.ub.uni-heidelberg.de/volltextserverhttps://archiv.ub.uni-heidelberg.de/volltextserver/8595/1/Xin_1982_EMBOJ.pdf
identifier: DOI:10.11588/heidok.00008595
identifier: urn:nbn:de:bsz:16-opus-85956
identifier:   Xin, J.-H. ; Kvist, S. ; Dobberstein, B.  (1982) Identification of an H-2Kd gene using a specific cDNA probe.  The EMBO Joumal, 1 (4).  pp. 467-471.      
relation: https://archiv.ub.uni-heidelberg.de/volltextserver/8595/
rights: info:eu-repo/semantics/openAccess
rights: http://archiv.ub.uni-heidelberg.de/volltextserver/help/license_urhg.html
language: eng