Dissertation

Ahlmann-Eltze, Constantin (2023) Development of statistical methods for the analysis of single-cell RNA-seq data. [Dissertation]

Ahmels, Melinda (2023) Mastomys coucha as preclinical model to study macrophage-assisted DNA repair and cross-protecting L2 based vaccination in the same animal. [Dissertation]

Alonso de la Vega, Alicia (2023) Uncovering the role of APOBEC3B in lung cancer and RNA editing. [Dissertation]

Alvarado Valverde, Jesús (2023) Computational prediction of Short Linear Motif candidates in the proteome of the Apicomplexan parasite Toxoplasma gondii. [Dissertation]

Andresen, Carolin (2023) Multi-omics analysis of DNMT3A- and NPM1-mutated acute myeloid leukemia. [Dissertation]

Araujo Sousa, Carolina (2023) Analysis of neuroactive peptides on mouse hypothalamic thermoregulation. [Dissertation]

Athanasiou, Christina (2023) Modeling of mechanistic effects of neurotrophin modulators. [Dissertation]

Baccianti, Francesco (2023) Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response. [Dissertation]

Barriuso Ortega, Isabel (2023) Space, time and item coding in the lateral entorhinal cortex and the hippocampus. [Dissertation]

Baur, Katja (2023) Apical Neural Stem Cells and the Effect of Growth/Differentiation Factor 15 on their Primary Cilia and Proliferation. [Dissertation]

Becker, Jonas (2023) Pulling the right viral levers: Engineering, screening and application of next-generation combinatorial AAV vectors. [Dissertation]

Beumers, Lukas (2023) Clonal heterogeneity of endocrine therapy resistance in breast cancer. [Dissertation]

Blume, Christina (2023) Characterization of inter- and intratumoral heterogeneity and the differential immune microenvironment during malignant progression in meningiomas. [Dissertation]

Boga, Eren (2023) Generation of a cellular library of CAR T cells for rapid screening and identification of antigen specific, functional CAR constructs. [Dissertation]

Bondarenko, Vladyslav (2023) Coordination Mechanisms of Mammalian Embryo Implantation. [Dissertation]

Bordas, Marie (2023) Deciphering the role and the mechanism of B- cell Non-Hodgkin Lymphoma-derived small Extracellular Vesicles in modulating the phenotype of myeloid cells. [Dissertation]

Boskovic, Pavle (2023) The dual role of BCAT1 in glioblastoma: a metabolic enzyme with a twist. [Dissertation]

Bufe, Anja (2023) The roles of Wnt signaling during mitosis. [Dissertation]

Damerow, Helen Maraike (2023) Vergleichende Untersuchung von 89Zr-Chelatoren im Hinblick auf ihre Eignung in der Immuno-PET und Evaluierung eines neuen bifunktionellen cross-bridged-Chelators für 68Ga. [Dissertation]

Damo, Elisa (2023) Activation of beta2-adrenergic receptors alleviates neuropathic pain hypersensitivity in mice: focus on spinal glial cells. [Dissertation]

Demerdash, Yasmin (2023) The Transcriptional Landscape of Hematopoietic Stem and Progenitor Cells during Acute Inflammatory Stress. [Dissertation]

Derani, Judith Magdalena (2023) Combining Radiation and Oncolytic Measles Virus for the Treatment of Refractory Tumors. [Dissertation]

Doldan, Patricio (2023) Live-cell microscopy analysis of rotavirus-infection spread and its associated innate immune response in human intestinal epithelial cells. [Dissertation]

Fakhr, Elham (2023) Identification and characterization of T cell receptors reactive to the E7(11-19) epitope of HPV-16. [Dissertation]

Falkenstein, Kristina (2023) Charakterisierung einer neuen SLC35A1-Mutation bei einer Patientin mit Glykosylierungs- und Stoffwechseldefiziten. [Dissertation]

Feuerstein-Akgöz, Clarissa (2023) Integrated multi-omic dynamics of human adipocyte differentiation with focus on DNA hydroxymethylation and epigenomic effects of long-term docosahexaenoic acid treatment. [Dissertation]

Frank, Lukas (2023) Perturbing and imaging nuclear compartments to reveal mechanisms of transcription regulation and telomere maintenance. [Dissertation]

Frese, Lukas (2023) Population relevance of neurotoxic effects in refined and alternative behavior tests with zebrafish (Danio rerio). [Dissertation]

Friske, Marion Monika (2023) Transcriptomic Signatures in Alcohol Use Disorder - A Translational Approach. [Dissertation]

Fuchs, Michael (2023) Quantitative approaches towards understanding cell-to-cell mobility of the homeodomain transcription factor WUSCHEL (WUS) in the Arabidopsis thaliana shoot apical meristem. [Dissertation]

Gallo, Elisa (2023) FGF signaling and cell state transitions during organogenesis. [Dissertation]

Garbowicz, Karolina Aleksandra (2023) Exploring Ferroptosis as a Novel Liability of High-Risk Neuroblastomas. [Dissertation]

Garg, Niharika (2023) Role of Non-Muscle Myosin II in the Morphogenesis of Nematocysts in Hydra. [Dissertation]

Gege, Olatunji Oluwole (2023) Elucidating the Functional Relevance of BAP1 in the Liver. [Dissertation]

Gillich, Nadine (2023) Role of LGP2 in the Innate Immune System upon Viral Infections. [Dissertation]

Gopalan, Anusha (2023) The role of lipids in development and the control of cellular mechanics. [Dissertation]

Grieshober, Denise (2023) The role of the N-fragment of Angiopoietin-like 4 during malignant melanoma metastasis formation. [Dissertation]

Göllner, Sarah (2023) Functional and biochemical characterization of viral and host factors involved in the Zika virus replication cycle. [Dissertation]

Haas, Aylin Sibel (2023) Gene Regulatory Networks in Plant Stem Cells - Investigating cell fate decision-making in the vascular cambium of Arabidopsis. [Dissertation]

Hadzic, Armin (2023) Heterogeneity and multi-omics features of alternative lengthening of telomeres. [Dissertation]

Han, Ju Yeon (2023) To what extent is digit patterning a Turing System? [Dissertation]

Hong, Chen (2023) Analysis of whole-genome sequencing data from ICGC-PanCancer project. [Dissertation]

Hunger, Jessica (2023) Non-invasive tracking of T cell recruitment to the tumor microenvironment in a murine glioma model by high field cellular magnetic resonance imaging. [Dissertation]

Höps, Wolfram Gregor Alexander (2023) Genomic diversity associated with polymorphic inversions in humans and their close relatives. [Dissertation]

Hörner, Sarah Janice (2023) Optimized differentiation of hiPSC-derived Schwann cells and their integration into 2D and 3D neuromuscular tricultures. [Dissertation]

Ionasz, Vivien-Sandra (2023) Elucidating the role of transcription in recurrent DNA break formation. [Dissertation]

Jamaladdin, Nora (2023) The role of key pharmacodynamic and pharmacokinetic parameters in drug response prediction of pediatric tumors in the precision oncology study INFORM. [Dissertation]

Janocha, Denis (2023) Metabolic regulation of the shoot apical meristem by the TOR kinase in Arabidopsis thaliana. [Dissertation]

Joshi, Pooja (2023) Impact of a single nucleotide polymorphism in the CD40 gene and diabetes-associated stress factors on endothelial dysfunction. [Dissertation]

Juarez Altuzar, Janathan Michael (2023) Development, characterization and application of lysosome-targeted multi-functional sphingosine and cholesterol probes. [Dissertation]

Judmann, Benedikt Georg Florian (2023) Design, Synthese und vergleichende Untersuchung von Mono- und Multimeren EGFR (Epidermal Growth Factor Receptor)-spezifischer Peptide hinsichtlich ihrer Eignung für die Bildgebung maligner Zellen. [Dissertation]

Kahloon, Masroor Ahmad (2023) The role of Exon Junction Complex (EJC) and SOLE in oskar mRNA transport. [Dissertation]

Kandala, Sridhar (2023) Chronic chromosome instability induced by Plk1 results in immune suppression in breast cancer. [Dissertation]

Kaya, Oguzhan (2023) Wnt Signaling Modulates Normal and Malignant Stem Cell Activation in the Adult Brain. [Dissertation]

Keles, Merve (2023) Secreted long non-coding RNAs Gadlor1 and Gadlor2 act as mediators of cardiac remodelling during pressure overload. [Dissertation]

Khorani, Karam (2023) Unraveling Druggable Key Nodes in Gene Regulatory and Signaling Networks by Integrative Analysis of Multi-omics Data from Head and Neck Cancer. [Dissertation]

Kikul, Frauke (2023) The influence of membrane lipids on glycosylation processes: Activity of Dpm1 in different lipid environments. [Dissertation]

Klein, Steffen (2023) In situ cryo-correlative light and electron tomography of influenza A virus entry and its inhibition by IFITM3. [Dissertation]

Knudsen, Arne (2023) Alternative pre-mRNA splicing as a source of cancer neoepitopes. [Dissertation]

Koch, Robin-André (2023) Time-resolved analysis of cell colony growth in vitro after irradiation. [Dissertation]

Kreibich, Elisa (2023) Epigenetic regulation of enhancer activity in the mammalian genome. [Dissertation]

Kremer, Lukas Peter Maria (2023) Investigating the Molecular Basis of Adult Neurogenesis: Single-Cell Multi-Omics Unveils DNA Methylation as a Key Regulator of Astrocyte Stemness. [Dissertation]

Kromm, Dimitri (2023) Pushing Light-Sheet Microscopy to Greater Depths. [Dissertation]

Krämer, Stephen Jörg (2023) Uncovering the mechanisms and information content of CpG-resolved DNA methylation programming during hematopoietic differentiation. [Dissertation]

Kuehn, Naëmi (2023) Kainic acid-induced lumbar spinal cord damage leads to coordination deficits for the examination of cellular replacement therapies. [Dissertation]

Kuodytė, Karolina (2023) The Golgi complex as a regulatory platform for DNA Damage Response pathways. [Dissertation]

Kupke, Janina (2023) DNA methylation and transcriptional control in memory formation, persistence and suppression. [Dissertation]

Lampropoulos, Athanasios (2023) Biochemical and molecular characterisation of the transcription factor WUSCHEL in Arabidopsis thaliana. [Dissertation]

Langova, Ralitsa (2023) Multi-omics of AML. [Dissertation]

Lanzer, Jan David (2023) From Mouse Models to Patients: A Comparative Bioinformatic Analysis of HFpEF and HFrEF. [Dissertation]

Lehmann, Nadja (2023) Development of axon-carrying dendrite cells in murine hippocampus and primary somatosensory cortex. [Dissertation]

Leiß, Kevin (2023) Development and Evolution of the Mammalian Cerebellum at Single Cell Resolution. [Dissertation]

Li, Hongxiang (2023) The functional evolution of photolyase related to DNA repair and circadian clock in vertebrates. [Dissertation]

Li, Xin (2023) Endoplasmic reticulum stress sensor ATF6 as an immunometabolic modulator in hepatic tumorigenesis. [Dissertation]

Lindner, Katharina (2023) Identification and validation of neoepitope-specific T cell receptors for glioma immunotherapy. [Dissertation]

Lokumcu, Tolga (2023) Metabolic, proteomic, transcriptomic, and fatty acid profiling of glioblastoma stem cells and their small extracellular vesicles. [Dissertation]

Lomoschitz, Andrea (2023) Structural and RNA binding studies of Hrp48 – a regulator of translation in female Drosophila dosage compensation. [Dissertation]

Mangei, Jasmin Elena (2023) Exploring therapeutic vulnerabilities in tumours with GLI1 oncogene activation. [Dissertation]

Mathioudaki, Anna (2023) Deciphering the Interplay of Acute Myeloid Leukemia with the Bone Marrow Microenvironment. [Dissertation]

Michels, Tillmann (2023) A high-throughput RNAi screening identifies olfactory receptor signaling as a novel immune checkpoint in solid tumors. [Dissertation]

Misiaszek, Agata Dorota (2023) Structural studies of the human RNA polymerase I and the role of human RNA polymerase I and III in diseases. [Dissertation]

Müller, Iris (2023) Inhibiting glucocorticoid receptor signalling in tumour-associated macrophages for anti-tumour immune response. [Dissertation]

Najafian Jazi, Maryam (2023) Hippocampal representations of homing based on path integration. [Dissertation]

Nebioglu, Firat (2023) HOST FACTORS ASSOCIATED WITH HEPATITIS B VIRUS LIFE-CYCLE: INSIDE AND OUT. [Dissertation]

Oktriani, Risky (2023) The discovery of genes that exhibit strong effects on metastatic pancreatic cancer. [Dissertation]

Papagrigorakes, Marianne (2023) Tools to study cytoadhesion of P. falciparum-infected erythrocytes under flow. [Dissertation]

Pham, Minh Tu (2023) Intercellular transmission of viral RNA by Apolipoprotein E-associated extracellular vesicles. [Dissertation]

Ramirez Flores, Ricardo Omar (2023) Multi-scale molecular descriptions of human heart failure using single cell, spatial, and bulk transcriptomics. [Dissertation]

Ren, Yonggang (2023) Studies of Jmjd6 in embryogenesis and ISL1 phosphorylation in cardiac development. [Dissertation]

Richtmann, Sarah (2023) The role of the pregnancy-associated protein glycodelin and its influence on the immune system in non-small-cell lung cancer. [Dissertation]

Rivera Krstulovic, Catalina (2023) Role of vascular Dnmt3a during adult homeostasis and disease-associated vascular re-activation. [Dissertation]

Rose, Fabian (2023) A pan-cancer long non-coding RNA (lncRNA) signature defines oncogene activity in blood serum of cancer patients. [Dissertation]

Rosenkranz, Micha Tobias (2023) Old but gold: The Plasmodium falciparum merozoite surface protein 1 is still a promising blood stage vaccine candidate. [Dissertation]

Rösch, Lisa (2023) ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma through P-glycoprotein. [Dissertation]

Saharuka, Veronika (2023) Application of MALDI mass spectrometry for spatially resolved, untargeted metabolomics. [Dissertation]

Sanghvi, Khwab (2023) Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas. [Dissertation]

Sarropoulos, Ioannis (2023) Non-coding genome contributions to the development and evolution of mammalian organs. [Dissertation]

Schmenger, Torsten (2023) Exploration of Natural Variants in Human Health and Disease. [Dissertation]

Schmid, Theresa (2023) BCAT1 is a novel target of MLL fusions and essential for leukemic stem cell transformation. [Dissertation]

Schütz, Sabrina (2023) Characterization of cancer-associated fibroblast heterogeneity in squamous cell carcinoma progression using single-cell RNA sequencing. [Dissertation]

See, Jia-Xiang (2023) Immune-endothelial axis in liver homeostasis and inflammation. [Dissertation]

Siekmann, Marco Torben (2023) Organoid assembloids modelling the role of serotonin during human cortical development. [Dissertation]

Snajder, Rene Helmut (2023) Methods for Epigenetic Analyses from Long-Read Sequencing Data. [Dissertation]

Steinfass, Tamara (2023) The influence of secretogranin 2 on the assembly and presentation of the MHC class I complex in melanoma. [Dissertation]

Steyn, Sheldon (2023) Investigating the role of BPLF1 in the EBV life cycle. [Dissertation]

Sun, Xueyuan (2023) Investigating New Drug Options for Temozolomide Resistant IDH1 Mutant Glioma. [Dissertation]

Teschner, Annkathrin Chiara (2023) Use of TCR antibody fusion proteins as bispecific agents for NK and T cell-mediated immunotherapy. [Dissertation]

Tschanz, Aline (2023) A nanoscopic reconstruction of clathrin coat remodeling during mammalian endocytosis. [Dissertation]

Utsho, Ali Haider (2023) Depletion of Insulin Receptors leads to Metabolic alteration and Microvascular complications in zebrafish. [Dissertation]

Vaishali, Vaishali (2023) Characterisation of RNA binding proteins and their roles in the Drosophila germline. [Dissertation]

Varma, Eshita (2023) mRNA Binding Proteins in the Heart. [Dissertation]

Volpin, Valentina (2023) A screening for novel immune-checkpoints identifies CAMK1D as a kinase responsible for immune resistance in multiple myeloma. [Dissertation]

Voß, Yannik (2023) The role of phase separation in centrin interactions during Plasmodium falciparum schizogony. [Dissertation]

Wang, Yuanyuan (2023) Plasmatic von Willebrand factor regulates hematogenous metastasis of melanoma cells through its binding to heparan sulfate. [Dissertation]

Wassmer, Guillaume Emmanuel (2023) Antigen-armed antibodies (AgAbs) in the treatment of Acute Myeloid Leukemia (AML). [Dissertation]

Weigel, Bettina (2023) The role of MYT1L in the aetiology of neurodevelopmental disorders. [Dissertation]

Weller, Céline (2023) Pre-metastatic and immunological conditioning of the hepatic niche during melanoma progression. [Dissertation]

Willnow, Philipp (2023) Nuclear positioning and a non-uniform metabolism exert epigenetic control of gene expression in the wing disc. [Dissertation]

Winter, Sophie Luise (2023) Structural characterization of Ebola virus uncoating. [Dissertation]

Wohlfart, Sabrina (2023) Synthese und präklinische Evaluation von Peptid-Gallensäure-Chimären als antivirale Wirkstoffe gegen HBV/HDV. [Dissertation]

Yuan, Cheng (2023) Analysis of the role of Wnt signaling activation in ciliogenesis. [Dissertation]

Zanotti, Andrea (2023) Characterisation of the human signal peptidase complex as a quality control enzyme for membrane proteins. [Dissertation]

Zeuch, Stephanie Tanja (2023) Identification of novel substrates of the Insoluble Protein Deposit (IPOD) in the yeast S. cerevisiae. [Dissertation]

Zhang, Kaiqing (2023) The role of WNT/STOP signaling during neurogenesis and ciliogenesis. [Dissertation]

Zheng, Tuyu (2023) Analysis of Oncogenic Drivers in Supratentorial Brain Tumors. [Dissertation]

Zhong, Jiaxin (2023) Stress-induced degradation of inulin in Cichorium intybus: Exploring the transcriptional regulation of Fructan 1-exohydrolases. [Dissertation]

Zinchenko, Valentyna (2023) How to describe a cell: a path to automated versatile characterization of cells in imaging data. [Dissertation]

Zottnick, Samantha (2023) Assessment of methods to direct T cells toward a newly established HPV16 E6/E7-dependent orthotopic tumor model in A2.DR1 mice. [Dissertation]

Zuza, Kristina (2023) Characterization of mouse preoptic area cellular populations involved in thermoregulation. [Dissertation]

Özbay Kurt, Feyza Gül (2023) Targeting MDSC-mediated immunosuppression in melanoma. [Dissertation]

Book Section

Lehmann, Rosa ; Giurca, Alexandru (2023) Bioökonomie. [Book Section]

Meier, Thomas (2023) Raum. [Book Section]