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Up a levelKoch, Jonas Martin Maria (2023) Mechanistic modeling and scale-up investigation of a preparative two-column purification step for a biopharmaceutical polypeptide.
Nürnberg, Elina (2023) Optimizing Microscopy in Three Dimensions: Optical Clearing Techniques for the Study of hiPSC-Derived Neural Spheroids and 3D Cell Cultures.
Schäfer, Maximilian E. A. (2022) Microscopic study of RNA-lipoplex-mediated cell targeting using 2D and 3D models.
Seelinger, Felix (2022) Complex binding and elution behavior of therapeutic proteins under column overloading conditions.
Stange, Carolin (2023) Characterization of excipients for their application during purification of monoclonal antibodies and other therapeutic proteins.
Keller, Florian (2021) Targeted 2D- and 3D-cell cultures reveal mechanistic effects of extracellular matrix and stromal cells on the metastatic niche formation and metabolism of cancer cells.
Mende, Tatjana (2022) Development and Application of a Proximity Ligation Assay for the Quantification of Synaptic Density in Mouse Models of Alzheimer’s Disease.
Reyes, Gabriela Sánchez (2021) Separation and characterization of antibody-based protein variants in column chromatography for the publication of biopharmaceuticals.
Uhler, Rico (2021) Glyco-engineered HEK 293-F cell lines to produce therapeutic glycoproteins with human N glycosylation and improved pharmacokinetics.
Hahnel, Wojciech (2020) Extraction of DNA from difficult samples with an automatable portable system for early detection of intestinal cancer.
Rustamov, Valeh (2019) Charakterisierung eines neuen therapeutischen Antikörpers gegen das Knochensialoprotein durch Analyse in der 3D Zellkultur im Vergleich zur 2D Zellkultur.
Kowalski, Alexandra (2020) Development of a quick, robust and chemically-defined differentiation protocol from human induced pluripotent stem cells towards cortical neurons to phenotype Alzheimer’s Disease.
Klicks, Julia (2019) Development and characterization of a novel, simple, spheroid-based tri-culture model composed of fibroblasts, keratinocytes, and melanoma cells.
Zeinali, Mina (2019) Isolation, characterization, and expansion of heterogeneous circulating tumor cell (CTC) populations from cancer patients using microfluidic technologies.
Wittkopp, Felix (2018) Untersuchung systematischer Zusammenhänge zwischen Chromatographie-Gel Eigenschaften und Antikörper-spezifischen Verunreinigungen in der Säulenchromatographie.
Honarnejad, Saman (2017) Dissecting population and single-cell heterogeneity in response to anti-cancer drugs.
Kluters, Simon (2016) Modeling of pH and solvent modulated chromatography for the purification of biopharmaceuticals.
Lee, Yi Feng (2015) Improvement of monoclonal antibody drugs by selective removal of immunogenic contaminants like multimers and host cell proteins.
Werk, Tobias (2016) Optimization of heat and mass transfer, elucidation of reconstitution factors and assessing opportunities for liquid-liquid combination applications in dual chamber systems.
Böser, Preethne (2014) Characterization of anti-RGMa/c mAbs and their influence on iron regulation.
Förg, Tassilo (2015) Investigation of a possible dominant negative effect of endoglin missense mutations in Morbus Osler / Hereditary Hemorrhagic Telangiectasia (HHT).
Perrin, Jessica (2015) Development and Application of in vitro Assays for the Identification and Characterization of Kinase Inhibitors.
Schwamb, Sebastian (2015) MALDI-TOF Massenspektrometrie Biotyping – at-line Analyse von rekombinanten Zelllinien.
Ponce Moya, Leslie (2014) Establishment and characterization of an in vitro coculture model to study functional interaction between porcine keratinocytes and sensory neurites involved in cutaneous nociception.
Schmidt, Michael (2014) Entwicklung effizienter Aufreinigungsstrategien für therapeutische Biomoleküle.
Schwarz, Julia (2014) Aufklärung der Biosynthese des Antibiotikums Roseoflavin aus dem Bakterium Streptomyces davawensis.
Blech, Michaela (2012) Structural and biophysical characterization of antigen : antibody binding interfaces and their potential biological implications in GM CSF and interleukin-1β signaling.
Seeland, Swen (2012) How in vitro alterations in cellular energy pathways can overcome obstacles in drug research.
Jankowitsch, Frank (2012) Die beiden terminalen Schritte der Roseoflavin-Biosynthese in Streptomyces davawensis werden von einer bisher unbekannten N,N-8-Amino-8-demethyl-D-riboflavin Dimethyltransferase (RosA) katalysiert.
Lechner, Anna (2011) Regulation and genetic engineering of salinosporamide A biosynthesis.
Rey-Giraud, Flora (2012) Characterization of M-CSFR in tumorigenesis and the interactions between tumor cells and monocyte-derived macrophages in vitro.
Urmann, Marina (2011) Einfluss der Oberflächenmodifikation stationärer Phasen auf Protein-Matrix-Wechselwirkungen und Massentransportprozesse in der Ionenaustauschchromatographie.
Choi, Kyeong Rok (2010) Regulation of Synaptic Plasticity in Skeletal Muscle.
Koziolek, Eva Jolanthe (2011) In vitro and in vivo evaluation of a high affinity ErbB4 receptor based ligand trap.
Potempa, Marc (2010) Untersuchungen zur oxidativen in vitro Proteinrückfaltung unter Verwendung von Gemini-Disulfiddetergenzien.
Stahl, Heiko (2009) Identifizierung und funktionelle Charakterisierung von miRNAs und Oberflächenrezeptoren spezifisch für regulatorische T-Zellen.
Hudler, Melanie (2008) Identifizierung eines neuen Kandidaten-Onkogens.
Martinez, Rafael (2008) Universal microarray for analysis of breast cancer.
Mücke, Norbert (2008) Biophysikalische Untersuchung des muskelspezifischen Intermediärfilament-Proteins Desmin und Mutanten.
Giehl, Michelle (2006) Zentrosomenaberrationen und genetische Instabilität im Verlauf der chronischen myeloischen Leukämie.
Grill, Simon (2007) Riboflavin-Biosynthese und Roseoflavin-Resistenz im Gram-positiven Bodenbakterium Streptomyces davawensis.
Holloschi, Andreas (2007) Chorea Huntington: Zelluläres in vitro-Modell der polyglutaminabhängigen Proteinaggregation.
End, Caroline (2006) Untersuchungen zur Funktionsweise von Deleted in Malignant Brain Tumors 1 in der Erkennung und Abwehr von Pathogenen.
Kemmling, Andre (2006) Kupfer und die Alzheimersche Erkrankung: ein molekularer Link zum Amyloid-Vorläufer-Protein APP.
Maurer, Andreas Nikolas (2006) Interaktion von Chondrozyten mit Komponenten der extrazellulären Matrix : Einfluss von Erkrankung und Dedifferenzierung.
Treiber, Carina (2004) Studien zur Metallionenhomöostase des Amyloid-Vorläuferproteins und des Prion-Proteins in vivo.
Bauer, Andrea (2003) Genexpressionsanalysen in Karzinomen des Pankreas mittels DNA-Microarray-Technologie.