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The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand

Wilder-Smith, Annelies ; Byass, Peter ; Olanratmanee, Phanthip ; Maskhao, Pongsri ; Sringernyuang, Luechai ; Logan, James G. ; Lindsay, Steve W. ; Banks, Sarah ; Gubler, Duane ; Louis, Valérie R. ; Tozan, Yesim ; Kittayapong, Pattamaporn

In: Trials, 13 (2012), Nr. 212. pp. 1-7. ISSN 1468-6694

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Download (248kB) | Lizenz: Creative Commons LizenzvertragThe impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand by Wilder-Smith, Annelies ; Byass, Peter ; Olanratmanee, Phanthip ; Maskhao, Pongsri ; Sringernyuang, Luechai ; Logan, James G. ; Lindsay, Steve W. ; Banks, Sarah ; Gubler, Duane ; Louis, Valérie R. ; Tozan, Yesim ; Kittayapong, Pattamaporn underlies the terms of Creative Commons Attribution 3.0 Germany

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Abstract

There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. Methods: A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7–18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. Discussion: Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. Trial registration clinicaltrial.gov. Registration number: NCT01563640

Item Type: Article
Journal or Publication Title: Trials
Volume: 13
Number: 212
Publisher: BioMed Central
Place of Publication: London
Date Deposited: 26 May 2015 13:00
Date: 2012
ISSN: 1468-6694
Page Range: pp. 1-7
Faculties / Institutes: Medizinische Fakultät Heidelberg > Institut für Public Health (IPH)
Subjects: 370 Education
610 Medical sciences Medicine
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