In: Journal of Cardiothoracic Surgery, 10 (2015), Nr. 87. S. 1-8. ISSN 1749-8090

Vorschau

PDF, Englisch Download (2MB) | Lizenz: Resection of thoracic malignancies infiltrating cardiac structures with use of cardiopulmonary bypass von Arif, Rawa ; Eichhorn, Florian ; Kallenbach, Klaus ; Seppelt, Philipp ; Ruhparwar, Arjang ; Dienemann, Hendrik ; Karck, Matthias steht unter einer Creative Commons Namensnennung 3.0 Deutschland

Abstract

Background: Only few reports exist on malignant thoracic neoplasms that require cardiopulmonary bypass during resection. We aimed to investigate the early and late clinical outcome of these patients. Methods: Patients with thoracic malignancies that underwent surgery between 2002 and 2014 were analyzed. All patients had cardiopulomonary bypass support during resection. Clinical and perioperative data was retrospectively reviewed for outcome and overall survival. Results: Fifteen patients (12 female, mean age of 55 ± 15 years, range 24 to 80 years) were identified. Eleven (8 female) were diagnosed with primary thoracic malignomas and four with metastases. Three patients died early postoperatively. Patients diagnosed with sarcoma had a significantly worse outcome than non-sarcoma patients (83.3 ± 15.2 % after 1 year, 31.3 ± 24.5 % after 5 years vs. 83.3 ± 15.2 % after 1 year, 0 ± 0 % after 5 years, p = 0.005). Conclusions: Malignancies with extension into cardiac structures or infiltration of great vessels can be resected with cardiopulmonary bypass support and tolerable risk. Carefully selected patients can undergo advanced operative procedures with an acceptable 1-year-survival, but only few patients achieved good long-term outcome.